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Further Data from Phase 2 Statins Trial in Progressive MS Show Effect on Cognition: Phase 3 Study Underway

June 9, 2017

New data have been published from a completed phase 2 study of the cholesterol-lowering drug simvastatin in people with secondary progressive MS, indicating improvements in some aspects of cognitive function after 2 years among those given simvastatin. Previously reported results suggested that simvastatin reduced the rate of brain atrophy, or shrinkage.  A large phase 3 trial of simvastatin is underway, with co-funding from the National MS Society and others, being led by Dr. Jeremy Chataway (University College London).

Read more on the website of University College London Hospitals

Read the scientific paper, and the accompanying editorial

Read more about the phase 3 statins trial

 

About Multiple Sclerosis

Multiple sclerosis is an unpredictable, often disabling disease of the central nervous system that disrupts the flow of information within the brain, and between the brain and body. Symptoms range from numbness and tingling to blindness and paralysis. The progress, severity and specific symptoms of MS in any one person cannot yet be predicted, but advances in research and treatment are leading to better understanding and moving us closer to a world free of MS. Most people with MS are diagnosed between the ages of 20 and 50, with at least two to three times more women than men being diagnosed with the disease. MS affects more than 2.3 million people worldwide.

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