Society Researchers Push Technology Barriers to ID Novel Treatment Strategy - Drug Discovery and Development
May 8, 2014
Researchers from Harvard and University of California at San Francisco funded by the National MS Society, among others, report that they have identified three small molecules that can stop immune cells called Th17 cells, which play a role in the immune attacks against the brain and spinal cord in MS. Collaborators identified these molecules by looking at “transcription factors” that instruct the activity of genes. The team used genome-wide screening techniques to find transcription factors that activate Th17 cells, and then looked for ways to inhibit these factors. Read more at Drug Discovery and Development magazine.