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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Tysabri® (natalizumab)

    A multicenter, observational, open label study of to determine effectiveness in early relapsing remitting multiple sclerosis.
  2. Research Study: Generating Stem Cells for MS Research

    Investigators at The New York Stem Cell Foundation (NYSCF) Laboratory are recruiting 100 people with relapsing remitting, secondary progressive, and primary progressive forms of MS to undergo skin biopsies for the purposes of generating stem cell lines. 
  3. Clinical Trial: Siponimod (BAF312, Novartis Pharmaceuticals, AG)

    A multicenter, randomized, double-blind, parallel-group, placebo-controlled study evaluating the effectiveness and safety of siponimod (BAF312) in people with secondary progressive multiple sclerosis.
  4. Clinical Trial: Gilenya® capsules (fingolimod, Novartis Pharmaceuticals AG) versus Copaxone® (glatiramer acetate, Teva Pharmaceutical Industries, Ltd.

    A 12-month, randomized, blinded study to compare the effectiveness and safety of fingolimod 0.25 mg and 0.5 mg administered orally once daily with glatiramer acetate 20 mg administered subcutaneously once daily in patients with relapsing-remitting MS. 
  5. Clinical Trial: Home-Based Fall Prevention Program

    To examine the effectiveness of a home-based exercise program, an educational program and their combination on minimizing falls and fall risk.
  6. Clinical Trial: Extended-Release Baclofen

    A study to determine the effectiveness of extended-release baclofen capsules in relieving spasticity and symptoms related to MS. 
  7. Clinical Trial: Ballroom dance for persons with MS

    Pilot/Feasibility study to determine if partnered social dancing (i.e., ballroom dance) improves balance, stress, fatigue, or otherwise quality of life in persons with MS compared to a non-dance MS control group.
  8. Research Study: Investigators Seeking Tissue Samples Previously Obtained from People with MS and Similar Diseases

    In order to discover the triggers of MS, National MS Society-funded investigators at the University of Utah are seeking to collect existing brain biopsy tissue from individuals nationwide who underwent a brain biopsy to diagnose an episode of “acute demyelinating disease,...
  9. Clinical Trial: Exercise research study involving balance and eye movement training

    You may be eligible to participate if you: • have MS • experience some level of MS fatigue AND/OR some level of balance problems • are able to walk at least a city block (328 feet) with or without the help of a cane Research Study Involvement: • All el...
  10. Clinical Trial: Extended-Release Baclofen (1)

    A research study to evaluate the duration of action of Baclofen ER capsules in subjects with spasticity due to multiple sclerosis.

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