Participate in a Clinical Trial - National Multiple Sclerosis Society

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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.


Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials (.pdf)

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: rHIgM22, an experimental antibody

    Investigators nationwide are recruiting 30 people with MS for a phase I study to determine the safety and tolerability of rHIgM22, an experimental antibody. Participants may remain on their current therapy throughout the study. The study is enrolling participants experienc...
  2. Clinical Trial: Fingolimod

    The purpose of this world-wide prospective parallel-cohort study in patients with relapsing forms of MS, either newly treated with fingolimod or receiving another disease-modifying therapy, is to further explore the incidence of selected safety- related outcomes and to fur...
  3. Clinical Trial: Cognitive and Emotion Regulation Training in MS

    A randomized study of mindfulness meditation training compaired to an active cognitive training control group and waitlist control group in improving emotional regulation and attention in individuals with MS. Read more
  4. Clinical Trial: GET (Graduated Exercise Training) Smart Study

    The GET Smart study is looking at whether exercise has an impact on cognition in people with MS. Researchers at the University of Washington are studying exercise because other studies have shown that exercise can help cognition in other non-MS populations. However, curren...
  5. Clinical Trial: Fingolimod

    Patients with relapsing forms of multiple sclerosis either newly treated with fingolimod or treated with another approved disease-modifying therapy and switched to fingolimod.
  6. Clinical Trial: Keeogo Powered Dermoskeleton

    Open-label, comparative, randomized, cross-over, safety and efficacy study of the Keeogo powered dermoskeleton as an ambulation aid in individuals with walking disabilities.
  7. Clinical Trial: Water aerobics intervention

    This study will provide key insight into: 1) the immediate impact and durability of a one-week moderate intensity water aerobics intervention on cognition in this population, 2) the potential contribution of cerebral perfusion and fitness to cognitive changes, and 3) any p...
  8. Clinical Trial: Keeogo™ (motorized walking assistive device)

    A study to assess the use of a wearable lower body device to help knee control while walking.
  9. Clinical Trial: Exercise Training

    The study examines how brain function is improved by exercise. The study involves paper tests, fitness tests and an MRI scan (two sessions: baseline and follow-up), four group exercise classes at Kessler Foundation (one hour each), an individualized at-home exercise program (3...
  10. Clinical Trial: Clinical Trial: Methylphenidate

    This study examines the use of methylphenidate for persons with MS. This medication has been used to treat cognition, attention and fatigue in other neurological conditions such as Parkinson’s and traumatic brain injury. Kessler Foundation researchers want to see if this medic...


Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email to find out what information you need to submit for review.

Learn About Clinical Trials

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