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International Progressive MS Alliance

Connecting to end Progressive MS


International Progressive MS Alliance
In this article

What is the problem?

Progressive MS lacks a single, identifiable disease pattern. As a result, researchers lack the knowledge needed to focus and accelerate progress. And they lack tools to test how and why MS progresses, and too few new treatments are tested as a result of slow and costly trials. People with progressive MS need solutions now – every day they live with the very real possibility of losing ground.


More than 2.3 million people worldwide currently live with MS. More than half, over 1 million people, live with a progressive form of MS.

Progressive multiple sclerosis is a form of MS that gets worse over time. Each day, progressive MS takes things away from people: vision, mobility, cognition, ability to work, and their very independence. Despite advances in other forms of MS, there are no treatments for progressive MS.

The Progressive MS Alliance

The Progressive MS Alliance is a growing global initiative to end progressive MS. The Alliance began by bringing together the world’s leading experts in multiple sclerosis to identify the critical knowledge and treatment gaps where progress must be made to achieve breakthroughs necessary to change the world for people with progressive MS.

The Alliance is driving progress in three important ways

Global Leadership – ensuring that research is:

  1. Focused on barriers to treatment development
  2. Integrated across the MS community
  3. Systematically measured and refined


  1. Leveraging research already underway and stimulating new research and breakthroughs through a significant grants program.


  1. Drive worldwide resources to fund the best research, wherever it may be, and unleash the research community to accelerate results with the most impact and potential.

Members of the Alliance

  • Italian Multiple Sclerosis Association
  • Multiple Sclerosis Spain
  • MS Society UK
  • MS International Federation
  • MS Society of Canada
  • National MS Society
  • Scleroseforeningen

Learn More

Visit to learn more about work being done to end progressive MS.