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How Primary-Progressive MS is Treated

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At the present time, there are no medications that have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of PPMS. Because all of the approved disease-modifying therapies work primarily by reducing inflammation in the central nervous system (CNS), they do not work as well in a disease course that is characterized by nerve degeneration rather than inflammation.

Even without an approved disease-modifying therapy, however, there is a lot that people with PPMS and their health care team can do to manage the disease, including: