Glossary of Terms
Addison-Schilder disease (adrenoleukodystophy)
- A rare genetic disease characterized by a loss of myelin surrounding nerve cells in the brain and progressive adrenal gland dysfunction. It is a metabolic disorder combining the characteristics of Addison’s disease and cerebral sclerosis (Schilder disease).
- A disease in which the function or structure of the affected tissues or organs changes for the worse over time.
- Injury or loss of the myelin that surrounds nerve fibers and the primary cause of the symptoms associated with the disease
Plaque (also called a lesion or scar)
- An area of abnormality in the brain tissue seen on MRI.
Magnetic resonance imaging (MRI)
- A test that uses a magnetic field and pulses of radio wave energy to make pictures of organs and structures inside the body.
- A white material, composed of lipids (fats) and proteins, which surrounds and protects nerve fibers in the central nervous system, and serves as insulation to help speed nerve conduction.
- A disease or health condition that gets worse over time, resulting in a general decline in health or function. Unlike a relapsing and remitting disorder, there are not many periods of relief from a progressive disorder. Depending on the diagnosis, your progressive disorder may move quickly or slowly.