Although there is still no cure for MS, effective strategies are available to modify the disease course, treat exacerbations (also called attacks, relapses, or flare-ups), manage symptoms, improve function and safety, and provide emotional support. In combination, these treatments enhance the quality of life for people living with MS.
Modifying the Disease Course
The following agents can reduce disease activity and disease progression for many individuals with relapsing forms of MS, including those with secondary progressive disease who continue to have relapses.
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- Disease Management Consensus Statement (.pdf)
Recommendations and principles from the Society’s National Clinical Advisory Board for health care professionals and people with MS—to guide treatment with the disease-modifying drugs.
- The Disease-Modifying Drugs (.pdf)
A booklet describing the approved use, dosage and route of delivery, side effects, benefits, and available support programs.
- Patient Assistance Programs
A listing of the pharmaceutical company financial assistance programs to help manage the costs of the drugs.
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Treatment Locations
These clinical facilities have a formal affiliation with the National MS Society. The appropriate chapter clinical advisory committee, composed of MS experts, has reviewed and approved the affiliation.
Treating Exacerbations
An exacerbation of MS is caused by inflammation in the central nervous system (CNS) that causes damage to the myelin and slows or blocks the transmission of nerve impulses. To be a true exacerbation, the attack must last at least 24 hours and be separated from a previous exacerbation by at least 30 days. However, most exacerbations last from a few days to several weeks or even months. Exacerbations can be mild or severe enough to interfere with a person’s ability to function at home and at work. Severe exacerbations are most commonly treated with high-dose corticosteroids to reduce the inflammation.
Managing Symptoms
Symptoms of MS are highly variable from person to person and from time to time in the same individual. While symptoms can range from mild to severe, most can be successfully managed with strategies that include medication, self-care techniques, rehabilitation (with a physical or occupation therapist, speech/language pathologist, cognitive remediation specialist, among others), and the use of assistive devices.
Promoting Function through Rehabilitation
Rehabilitation programs focus on function—they are designed to help you improve or maintain your ability to perform effectively and safely at home and at work. Rehabilitation professionals focus on overall fitness and energy management, while addressing problems with accessibility and mobility, speech and swallowing, and memory and other cognitive functions.
Rehabilitation is an important component of comprehensive, quality health care for people with MS, at all stages of the disease. Rehabilitation programs include:
- Physical Therapy
- Occupational Therapy
- Therapy for Speech and Swallowing Problems
- Cognitive Rehabilitation
- Vocational Rehabilitation
The Role of Complementary and Alternative Medicine (CAM)
CAM includes everything from exercise and diet to food supplements, stress management strategies, and lifestyle changes. These therapies come from various disciplines and traditions—yoga, hypnosis, relaxation techniques, traditional herbal healing, Chinese medicine, macrobiotics, naturopathy, and many others. They are referred to as complementary when they are used in conjunction with conventional medical treatments and alternative when they are used instead of conventional treatments.
Treatment Updates
Change in Blood Donation Policy at American Red Cross
Apr 24, 2008
Until recently, people with MS were not permitted to donate blood at American Red Cross donation centers. The ban has now been lifted because no scientific evidence exists that MS is contagious or can be transmitted via blood. As of May, 2007, if other qualifications are met, blood from a person with MS may be donated to the American Red Cross.
Tysabri Label Changed To Reflect Potential Liver Damage
Feb 01, 2008
A letter went out to prescribers of Tysabri® (natalizumab, Biogen Idec and Elan Pharmaceuticals) from Biogen Idec and Elan Pharmaceuticals warning of an FDA-mandated label change that includes a new warning about the possibility of significant liver injury in people being treated with the drug. According to the new label, signs of liver injury, including markedly elevated serum hepatic enzymes and elevated total bilirubin, occurred as early as six days after the first dose, and have also been reported after multiple doses.
Low Dose Naltrexone Update
Jan 01, 2008
We have received a number of inquiries about the use of low dose naltrexone (LDN) as a treatment for multiple sclerosis. There are currently no published data from controlled clinical trials to support the use of naltrexone in MS. Further study is needed to determine if this is a safe and effective treatment for people with MS.
Guidelines for Administration of Human Papillomavirus (HPV) Vaccine (Gardasil®) to Multiple Sclerosis Patients
Nov 30, 2007
Gardasil® (Merck) is available as a prophylactic vaccine, designed to prevent the following conditions in girls and women 9 to 26 years of age: HPV 6, 11, 16 and /or 18-related cervical cancer, cervical dysplasias, vulvar and vaginal dysplasias, condyloma acuminata.
Flu Vaccine and MS
Oct 01, 2007
As in previous years, a flu shot is recommended as a safe and effective vaccination for people with MS. You can read about the Society's preventive care recommendations on the web site. The flu shot can safely be taken by individuals who are on a disease-modifying medication (Avonex®, Betaseron®, Copaxone®, Rebif®, or Tysabri®).