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Clinical Trials

Clinical Trials and Studies

People with MS can take an active role in freeing the world of MS by participating in drug studies. Visit our Frequently Asked Questions page for more information.

For assistance finding local clinical trials, please contact the Alabama-Mississippi Chapter MS specialist nearest you. Click Here for Alabama & Mississippi MS Specialists.


Local Clinical Trials

Tanner Center for MS - Birmingham, AL
Phone  205.803.2210

TYGRIS - Phase IV observational study in Patients taking Tysabri

STRATIFY - Study designed to screen for The JC antibody in MS patients to understand risk of PML with Tysabri

EPOC - Phase IV study assessing QOL in MS patients taking injectable therapy as compared to oral medication/Gilenya

BRAVO - Phase III study comparing oral medication/Laquinimod with Avonex

ARMS- Phase IV study to assess patients relapse symptoms and treatment response in terms of functioning

PRISM- Study designed to help to further the understanding of the prevalence and quality of life impact of Psedobulbar Affect (PBA)

STRIVE- Observational study examining the effects of Natalizamaub (Tsyabri) on disease progression in patients with early relapsing MS


National Clinical Trials

Investigators Recruiting for Study Comparing Exercise Programs to Improve Depression

Summary

Investigators at the University of Washington, Seattle, are recruiting 108 people with all types of MS or spinal cord injury nationwide for a study comparing the effects on depression of two telephone-coordinated exercise programs. The study, also called the inMotion study, is funded by the National Institutes on Disability and Rehabilitation Research.

After several baseline phone calls, and wearing an accelerometer ( a device that measures physical activity, similar to a pedometer) for seven days, participants will be randomly assigned to one of two groups. In Group A, a research study counselor will help participants to develop a personalized exercise program, based on individual motivation and need. The counselor also will provide six to eight follow-up phone counseling sessions, helping participants to raise motivation, track progress, problem solve, and make changes to the exercise program as needed.

In Group B, participants will receive one 60-minute phone session during which a counselor will review how to exercise safely and provide extra information on how to find exercises that suit individual needs. No follow-up counselor calls will be made to Group B. Both groups will receive three more questionnaire calls at Weeks 6, 12, and 24 of the study period.

Participants will be reimbursed for their time and for phone expenses up to $120.

Participant Criteria

Participants should be at least 45 years old, have MS or spinal cord injury, and should meet the criteria for major Depressive Disorder or chronic depression.

Contact

The inMotion Study, University of Washington
PO Box 356490, Seattle, WA 98195
1-866-928-2114
agerrtc@uw.edu

 

Genetics Study - UCSF

Summary

The UCSF MS Genetics Group is looking for participation of two types of families: single-case and multi-case families. More info.

Participant Criteria

Participants will be asked to:
- Fill out a family information form
- Sign a form to release medical records (people with MS only)
- Read and sign a consent and authorization form
- Donate a blood sample (about five tablespoons)

Contact

UCSF MS Genetics Group
1-866-MS-GENES or 1-866-674-3637
www.neurology.ucsf.edu

 

Research Banks

You can make a difference by arranging in advance to donate your brain and spinal cord tissues for research. The National MS Society supports three MS tissue banks, which are storage facilities that provide tissue samples to researchers studying MS. These studies generally focus on the pathology of MS - its nature, cause, and effects on the brain - and they are extremely important. Tissue samples are preserved very soon after the death of the donor. The banked tissues are carefully cataloged with information about the each donor's clinical history.

Those interested in the possibility of tissue donation may contact these banks:

Human Brain and Spinal Fluid Resource Center
West Los Angeles Health Care Center
Los Angeles, CA
310-268-3536 or 310-636-5199 (24-hour pager)

Rocky Mountain MS Center Tissue Bank
Englewood, CO
303-788-4030

 

Donate to MS Blood Repository of the Accelerated Cure Project

This repository - not funded by the National MS Society - also has been established to provide the scientific community with biological samples and data from people with MS and other demyelinating diseases. More info.