Currently Funded Research in Wisconsin
Funded by the National Multiple Sclerosis Society
BloodCenter of Wisconsin
Bonnie Dittel, Ph.D.
Term: 7/1/12-6/30/15
Funding: $450,431
“Regulation of EAE by CD86 expressed within the CNS” Investigating how an immune system signaling molecule suppresses MS-like disease for clues to new treatments to stop MS disease activity.
Bonnie Dittel, Ph.D.
Term: 10/1/2010-9/30/2013
Funding: $440,724
“Elucidating the role of cannabinoid receptor 2 in immune regulation during EAE” Looking at how cannabis-related molecules interact with and affect the immune system and their potential for turning off immune attacks.
University of Wisconsin-Madison
Colleen Hayes, Ph.D.
Term: 10/1/2010-9/30/2013
Funding: $585,146
“Vitamin D and estrogen synergy in the control of EAE” Exploring how vitamin D and the sex hormone estrogen may interact to control MS-like immune attacks and its implications for MS.
Colleen Hayes, Ph.D.
Term: 10/1/2009-9/30/2012
Funding: $485,469
“Calcitriol synthesis and IL-10-dependent function in the central nervous system” How vitamin D and vitamin D-derived hormone calcitriol may be used to prevent and treat an MS-like disease in mice for clues to its role in people with MS.
Julie Olson, Ph.D.
Term: 6/1/11-11/30/12
Funding: $44,000
“The role of NHE-1 on microglia during demyelinating disease” Investigating a molecule called “NHE-1” that may increase the immune attack in MS, and how inhibiting NHE-1 may reduce the activation of microglia (cells within the brain and spinal cord that participate in the immune attack in MS.
Recently Funded
University of Wisconsin-Madison
Aaron Field, M.D., Ph.D.
Term: 7/1/2010-6/30/2012
Funding: $586,436 CCSVI Grant
“Study of CCSVI in MS using quantitative time-resolved 3D MRV” Understanding the role of CCSVI (vein blockage) in MS and identifying optimal methods for screening for the condition.
John Fleming, M.D.
Term: 4/1/2005-3/31/2012
Funding: $567,110
“Helminth-induced immunomodulation therapy (HINT) in relapsing-remitting MS” A novel, pilot clinical trial testing whether ingestion of worm eggs has the potential to alter the immune attack in MS.