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How Primary-Progressive MS is Treated

At the present time, there are no medications that have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of PPMS. Because all of the approved disease-modifying therapies work primarily by reducing inflammation in the central nervous system (CNS), they do not work as well in a disease course that is characterized by nerve degeneration rather than inflammation.

Even without an approved disease-modifying therapy, however, there is a lot that people with PPMS and their health care team can do to manage the disease, including: