Signs & Symptoms Consistent With Demyelinating Disease

Signs & Symptoms Consistent with Demyelinating Disease [with links to information and resources for your patients]

Visual

blurred vision; unilateral loss of vision; oscillopsia; diplopia

Motor

Trunk/limb weakness; spasticity; hyperreflexia; gait disturbance; balance problems

Sensory

numbness; paresthesias; dysesthesias; Lhermitte’s sign; “MS hug”; trigeminal neuralgia; allodynia; hyperpathia; proprioception deficits

Cerebellar

tremor; ataxia; incoordination

Genitourinary

 

urgency/frequency/retention; incontinence; frequent UTI; constipation; impotence; anorgasmia; dyspareunia

Neuropsychiatric

impairment of memory, concentration, attention, and/or processing speed; depression; irritability; anxiety

Prominent intractable fatigue with no other cause

Similarly, there are certain features that are consistent with multiple sclerosis and others – red flags – that should prompt the clinician to consider other possibilities.