Multiple Sclerosis & COVID-19

Updated: March 26, 2024

Current evidence shows that simply having MS does not make you more likely than the general population to develop COVID-19, become severely ill or die from the infection. However certain factors, including some disabilities that may result from your MS, have been shown to increase the risk of a severe case of COVID-19:

• Progressive MS
• Older age
• Male sex
• Black race
• Using a mobility device or a wheelchair
• Obesity (body mass index of 30 or higher)
• Other chronic health conditions, like diabetes or heart disease, in addition to MS
• Taking steroid medications
• Taking certain disease modifying therapies called anti-CD20 monoclonal antibodies (Ocrevus and Rituxan and biosimilars)

See guidance for timing MS medications with COVID-19 vaccines. Learn more about who is at increased risk for severe illness from COVID-19 and check for updates from the Centers for Disease Control and Prevention (CDC).

You may have concerns about the future of COVID-19 and how to be ready if things change. Here is what you can do to stay prepared:

• Keep up to date with your COVID-19 vaccinations and consider the timing of your MS disease-modifying therapy.
• Follow CDC guidance for protecting yourself and others.
• Have good quality masks on hand and keep them with you when out in the community.
• Ensure the COVID-19 tests you’re using are currently authorized by the FDA.
• Learn where you can get testing and treatment in one location.

Contact your MS healthcare provider should you get diagnosed with COVID to see if treatment is recommended.

Pemgarda for pre-exposure prevention of COVID-19

The U.S. Food and Drug Administration (FDA) has authorized Pemgarda as a medication to prevent COVID-19 in some individuals age of 12 years and older. This prevention medication is strictly for those who are unlikely to have adequate immune responses to the vaccine.

Relapses are always a concern with MS and especially during COVID. Seek medical advice if you experience changes in your health that may suggest a relapse or another underlying issue, such as an infection. You may be able to manage your symptoms at home via telephone or video consultations.

During this time, use steroids only after careful consideration with a healthcare provider experienced in the treatment of MS and only for serious relapses. There is some evidence that receiving high-dose steroids in the month prior to contracting COVID-19 increases the risk of a more severe infection. If you receive steroid treatment for a relapse, be extra vigilant. You may want to consider self-isolating for at least a month.