Immune Cells from the Gut Can Turn Off Brain Inflammation in MS, Say Researchers Co-funded by the National MS Society
January 5, 2019
Researchers from San Francisco and Toronto have reported evidence that immune cells in the intestines can travel to the brain and release antibodies to control inflammation. The studies involved mice with MS-like disease and samples from people with MS. Future research will help to determine if this phenomenon can be harnessed as a therapy to stop immune attacks in MS. The researchers forged their collaboration, which was funded by the National MS Society and others, after reporting similar findings at a conference. If confirmed, these results may help to inform lifestyle questions, such as: do certain foods encourage these helpful cells to flourish? Can probiotics regulate the gut/brain immune interaction?
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View a scientific summary of the paper in Cell
Multiple sclerosis is an unpredictable disease of the central nervous system. Currently there is no cure. Symptoms vary from person to person and may include disabling fatigue, mobility challenges, cognitive changes, and vision issues. An estimated 1 million people live with MS in the United States. Early diagnosis and treatment are critical to minimize disability. Significant progress is being made to achieve a world free of MS.