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Immune Cells from the Gut Can Turn Off Brain Inflammation in MS, Say Researchers Co-funded by the National MS Society

January 5, 2019

Researchers from San Francisco and Toronto have reported evidence that immune cells in the intestines can travel to the brain and release antibodies to control inflammation. The studies involved mice with MS-like disease and samples from people with MS. Future research will help to determine if this phenomenon can be harnessed as a therapy to stop immune attacks in MS. The researchers forged their collaboration, which was funded by the National MS Society and others, after reporting similar findings at a conference.  If confirmed, these results may help to inform lifestyle questions, such as: do certain foods encourage these helpful cells to flourish? Can probiotics regulate the gut/brain immune interaction?
 
Read more from the University of California
View a scientific summary of the paper in Cell

About Multiple Sclerosis

Multiple sclerosis is an unpredictable, often disabling disease of the central nervous system that disrupts the flow of information within the brain, and between the brain and body. Symptoms range from numbness and tingling to blindness and paralysis. The progress, severity and specific symptoms of MS in any one person cannot yet be predicted, but advances in research and treatment are leading to better understanding and moving us closer to a world free of MS. Most people with MS are diagnosed between the ages of 20 and 50, with at least two to three times more women than men being diagnosed with the disease. MS affects more than 2.3 million people worldwide.

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