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Mouse Study Supports Idea that Repairing Nerve-Insulating Myelin Can Protect Nerves and Restore Function, Say Researchers Funded by National MS Society

October 7, 2016

Researchers from the University of California, San Francisco, along with an international team, showed that injecting the oral antihistamine clemastine into mice with MS-like disease resulted in myelin repair, protected nerve cells, and improved symptoms compared with untreated mice. The team did additional studies providing general support for the idea that finding a way to enhance natural myelin repair in MS may protect nerves from injury and help restore function. This study expands our understanding of the potential benefits of this compound, which has shown potential for stimulating myelin repair in people with MS, as well as other approaches aimed at enhancing myelin repair. The study was funded by the National MS Society among others.

Read more on the University of California, San Francisco website
Read the paper, published in eLife, an online journal
Read more about the pioneering work behind clemastine

About Multiple Sclerosis

Multiple sclerosis is an unpredictable, often disabling disease of the central nervous system that disrupts the flow of information within the brain, and between the brain and body. Symptoms range from numbness and tingling to blindness and paralysis. The progress, severity and specific symptoms of MS in any one person cannot yet be predicted, but advances in research and treatment are leading to better understanding and moving us closer to a world free of MS. Most people with MS are diagnosed between the ages of 20 and 50, with at least two to three times more women than men being diagnosed with the disease. MS affects more than 2.3 million people worldwide.

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