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New Study Reports on Possible Subset of MS

August 27, 2018

A new study by Cleveland Clinic investigators and other collaborators identified for the first time a subtype of MS that has not been previously appreciated. In a study of brain tissue obtained from people with MS via autopsy, a subset of 12 individuals had damage to nerve cells but not the destruction of nerve-insulating myelin typically seen in people with MS. At this time, it is not possible to detect this possible type of MS in individuals, or to determine how to best treat it.
 
If these findings are confirmed, the pathological differences detected in these studies may provide new insights for designing clinical trials and for treating people living with MS. These new observations highlight the need for improved, non-invasive imaging techniques that can help investigators and clinicians better understand tissue damage in MS and different types of disease activity.
 
This study was co-funded by the National Institutes of Health and the National MS Society.
 
Read more in Science Daily
 
Read the abstract of the study published in The Lancet Neurology

About Multiple Sclerosis

Multiple sclerosis is an unpredictable, often disabling disease of the central nervous system that disrupts the flow of information within the brain, and between the brain and body. Symptoms range from numbness and tingling to blindness and paralysis. The progress, severity and specific symptoms of MS in any one person cannot yet be predicted, but advances in research and treatment are leading to better understanding and moving us closer to a world free of MS. Most people with MS are diagnosed between the ages of 20 and 50, with at least two to three times more women than men being diagnosed with the disease. MS affects more than 2.3 million people worldwide.

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