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New Study Shows Links Between Stress and Disability/Relapses in MS

May 25, 2023

A survey of 713 people with MS adds to evidence of links between stress and both disability levels and relapses. Right now, people can take steps to reduce stress – see below.
  • Background: Stress is part of everyday life. The diagnosis of MS can sometimes make the stress of daily life feel overwhelming. Many people with MS say that during stressful times, they experience more or worse symptoms. When the stress decreases, their symptoms seem less troubling or less severe. Research is ongoing to determine the exact impact of stress on MS, and how these impacts can be reduced.
  • This Study: The research team from the University of Michigan gathered 713 responses to an online survey. Participants answered questions on stressors (events or situations that cause stress) before and after age 18, disability level, and relapse burden since the pandemic. Examples of stressors included physical/sexual/emotional abuse, neglect, poverty, divorce, neighborhood violence, witnessing domestic abuse, feeling excluded based on personal factors, and job loss.
  • Results: Participants reported an average of 2.6 stressors experienced during childhood, and an average of 23.6 experienced as an adult. The results show associations between childhood and adult stress and MS disability levels in adults. Adult stressors were associated with an increase in relapse burden since the pandemic.
  • The Meaning: These results show evidence of a connection between stress and MS. They present an opportunity to intervene and reduce stress levels. The authors are following up on this research to understand how the connection works – do other factors such as sleep, smoking, or mental health affect this link? Stress is a part of life, but people with MS can take steps right now to try to reduce it – see below.
Get help with stress: Associations among stressors across the lifespan, disability, and relapses in adults with multiple sclerosis” by Carri S. Polick, Robert Ploutz-Snyder, Tiffany J. Braley, Cathleen M. Connell, Sarah A. Stoddard is published in Brain and Behavior (First published: 21 May 2023).
 

About Multiple Sclerosis

Multiple sclerosis is an unpredictable disease of the central nervous system. Currently there is no cure. Symptoms vary from person to person and may include disabling fatigue, mobility challenges, cognitive changes, and vision issues. An estimated 1 million people live with MS in the United States. Early diagnosis and treatment are critical to minimize disability. Significant progress is being made to achieve a world free of MS.

About the National Multiple Sclerosis Society

The National MS Society, founded in 1946, is the global leader of a growing movement dedicated to creating a world free of MS. The Society funds cutting-edge research for a cure, drives change through advocacy and provides programs and services to help people affected by MS live their best lives. Connect to learn more and get involved: nationalMSsociety.org, Facebook, X, formerly known as Twitter, Instagram, YouTube or 1-800-344-4867.

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