Researchers Supported by the National MS Society Take Novel Gene-Immune Therapy Approach to Reverse Mouse Version of MS
September 23, 2017
Scientists at the University of Florida, funded in part by the National MS Society, took a novel approach to turn off immune attacks in mice with an MS-like disease. The team used a harmless virus to deliver a gene coding for a specific component of myelin, a key target of immune attacks in MS. This resulted in the activation of regulatory immune cells that suppressed the immune attack on the brain and spinal cord. This gene therapy approach prevented and reversed symptoms in the mice and was long-lasting. Further research is needed to verify and refine this approach before it can be tested in people.
Read about the study in University of Florida News
Read the original paper in Molecular Therapy
Read more about research aimed at stopping MS
Multiple sclerosis is an unpredictable disease of the central nervous system. Currently there is no cure. Symptoms vary from person to person and may include disabling fatigue, mobility challenges, cognitive changes, and vision issues. An estimated 1 million people live with MS in the United States. Early diagnosis and treatment are critical to minimize disability. Significant progress is being made to achieve a world free of MS.