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Researchers Supported by the National MS Society Take Novel Gene-Immune Therapy Approach to Reverse Mouse Version of MS

September 23, 2017

Scientists at the University of Florida, funded in part by the National MS Society, took a novel approach to turn off immune attacks in mice with an MS-like disease. The team used a harmless virus to deliver a gene coding for a specific component of myelin, a key target of immune attacks in MS. This resulted in the activation of regulatory immune cells that suppressed the immune attack on the brain and spinal cord. This gene therapy approach prevented and reversed symptoms in the mice and was long-lasting. Further research is needed to verify and refine this approach before it can be tested in people.
 
Read about the study in University of Florida News
Read the original paper in Molecular Therapy
Read more about research aimed at stopping MS

About Multiple Sclerosis

Multiple sclerosis is an unpredictable, often disabling disease of the central nervous system that disrupts the flow of information within the brain, and between the brain and body. Symptoms range from numbness and tingling to blindness and paralysis. The progress, severity and specific symptoms of MS in any one person cannot yet be predicted, but advances in research and treatment are leading to better understanding and moving us closer to a world free of MS. Most people with MS are diagnosed between the ages of 20 and 50, with at least two to three times more women than men being diagnosed with the disease. MS affects more than 2.3 million people worldwide.

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