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Small Study Suggests Benefit of Flavonoid-Rich Cocoa on Fatigue in People with MS

March 5, 2019

Researchers found that cocoa rich in flavonoids (plant chemicals that have anti-inflammatory and anti-oxidant properties) improved fatigue and walking speed in a small study of 40 people with MS, when compared with cocoa low in flavonoids. Some participants experienced worsening fatigue, feelings of nausea, or a general feeling of being unwell. The authors and an accompanying editorial suggest that a larger, longer-term study is warranted to help understand whether cocoa rich in flavonoids can be used alongside disease-modifying therapy and rehabilitation to help manage fatigue in MS.

Read more in a press release from the journal

Read the paper and editorial available free of charge in the Journal of Neurology, Neurosurgery, and Psychiatry

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Multiple sclerosis is an unpredictable, often disabling disease of the central nervous system. Symptoms range from numbness and tingling to blindness and paralysis, and there is currently no cure for MS. The progress, severity and specific symptoms of MS in any one person cannot yet be predicted, but advances in research and treatment are leading to better understanding and moving us closer to a world free of MS. An estimated 1 million people live with MS in the United States. Most people with MS are diagnosed between the ages of 20 and 50, and it affects women three times more than men.


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