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Society-Supported Researchers Find Possible Mechanism for Rare Seizures in People with MS

December 23, 2020

Seizures are not very common in people with MS, but occur more frequently than in the general population and may not respond well to traditional drug treatments. In an effort to understand the mechanism of seizures in people in MS, researchers at the University of California, Riverside, examined tissue samples obtained at autopsy from people with MS who had experienced seizures, and from people who did not. The team found signs that astrocytes, cells in the brain, were less able to regulate brain signals that might contribute to seizures in people who had them, when compared to those who did not.

These findings warrant further research to help pinpoint treatment strategies that reduce the incidence of seizures in people with MS.

This study was supported by the National MS Society and the National Institutes of Health.

Read more from the University of California, Riverside

Read the paper in ASN Neuro

About Multiple Sclerosis

Multiple sclerosis is an unpredictable, often disabling disease of the central nervous system. Symptoms range from numbness and tingling to blindness and paralysis, and there is currently no cure for MS. The progress, severity and specific symptoms of MS in any one person cannot yet be predicted, but advances in research and treatment are leading to better understanding and moving us closer to a world free of MS. An estimated 1 million people live with MS in the United States. Most people with MS are diagnosed between the ages of 20 and 50, and it affects women three times more than men.


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