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Study Shows Diet that Mimics Fasting Reduces Inflammation in Mice and is Well Tolerated in People with MS

May 29, 2016

Researchers from the U.S., Germany and Italy report that a diet that mimics fasting (involving cycles of several days in a row with limited caloric intake) reduced immune system activity and disease severity, and promoted regeneration of myelin-making cells in mice with MS-like disease. A small study of the diet in people with relapsing MS showed significant improvements in health-related quality of life, and was well tolerated and adhered to. "What we don't want is patients trying to do this at home without involvement of their specialist or without understanding that larger trials are necessary,” notes study author Professor Valter Longo (University of Southern California, Los Angeles). Co-author Dr. Laura Piccio (Washington University in St. Louis) was funded by a Harry Weaver Neuroscience Award from the National MS Society.

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Read the study from Cell Press
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About Multiple Sclerosis

Multiple sclerosis is an unpredictable, often disabling disease of the central nervous system that disrupts the flow of information within the brain, and between the brain and body. Symptoms range from numbness and tingling to blindness and paralysis. The progress, severity and specific symptoms of MS in any one person cannot yet be predicted, but advances in research and treatment are leading to better understanding and moving us closer to a world free of MS. Most people with MS are diagnosed between the ages of 20 and 50, with at least two to three times more women than men being diagnosed with the disease. MS affects more than 2.3 million people worldwide.

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