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Wisconsin Researchers Show that Thinly Repaired Myelin Sheaths Restore Nerve Function and Persist for Years

October 25, 2017

Myelin sheaths that encase nerve fibers are vital to nerve function and health. Finding ways to enhance the body’s ability to repair myelin that has been damaged by the MS disease process is a priority for restoring function. It has been known that repaired myelin is much thinner than the original sheath, but it wasn’t clear how well the repaired myelin could restore function. Now researchers funded by the National MS Society at the University of Wisconsin show that thinly repaired myelin sheaths are no lightweights: In fact, in models experiencing myelin damage, these sheaths persisted for years, and supported restored neurologic function. These findings may prove important in ongoing and future efforts to evaluate whether experimental therapies to promote myelin repair in MS are working.

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Read more from the journal Proceedings of the National Academy of Sciences, USA

Read more about repairing damaged tissue in MS

About Multiple Sclerosis

Multiple sclerosis is an unpredictable, often disabling disease of the central nervous system that disrupts the flow of information within the brain, and between the brain and body. Symptoms range from numbness and tingling to blindness and paralysis. The progress, severity and specific symptoms of MS in any one person cannot yet be predicted, but advances in research and treatment are leading to better understanding and moving us closer to a world free of MS. Most people with MS are diagnosed between the ages of 20 and 50, with at least two to three times more women than men being diagnosed with the disease. MS affects more than 2.3 million people worldwide.

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