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Clinical Study Measures


In this article

Overview and notes

A wide variety of measures have been used in clinical studies of MS. Provided here is information about many of those most frequently used. Each measure includes a brief description, administration time, administration method, scoring method, general comments, information on the psychometric qualities of the measure, and literature citations. In addition, where possible, the actual forms needed to utilize the measure are provided.

These measures are organized using the World Health Organization's International Classification of Functioning, Disability, and Health. The three major categories in the WHO system are

  1. impairments of body functions and body structures
  2. activity limitations and participation restriction
  3. environmental factors

For information on the WHO classification system, visit the ICF home page.

Questions concerning clinical study measures should be directed to the Vice President of Health Care Delivery and Policy Research at the National MS Society:

Nicholas LaRocca, PhD

All clinical study measures

Study measures for impairments of body functions and body structures

Study measures for activity limitations and participation restriction


© 2023 The National Multiple Sclerosis Society is a tax exempt 501(c)3 nonprofit organization. Its Identification Number (EIN) is 13-5661935.