Biotin is considered a form of vitamin B, and is a component of enzymes in the body that help break down certain substances in the body. Biotin, also known as vitamin H, is usually obtained from food.
In spring of 2015, an abstract was published of preliminary results
from a clinical trial in France involving 154 people with primary-progressive MS or secondary-progressive MS. They were given high-dose biotin (MD1003) or inactive placebo for 48 weeks. The results suggested that 12.6% of those given MD1003 showed improvement in disability (using either the EDSS scale that measures disability progression, or improvement in a timed walk), versus none of those on placebo, and there were no serious safety issues reported.
More research is needed to determine who might benefit from this approach. MedDay Pharma, which sponsored the trial, stated that another trial is underway.
: In November, 2017, the FDA issued a Safety Alert
to let the public and healthcare providers know that biotin can significantly interfere with certain lab tests, causing falsely high or falsely low test results that may go undetected. Talk to your doctor if you are currently taking biotin or are considering adding biotin, or a supplement containing biotin, to your diet. Biotin is found in multivitamins, including prenatal vitamins, biotin supplements and dietary supplements for hair, skin, and nail growth. Withholding biotin is often necessary before certain blood tests are done to avoid falsely abnormal results. It is important to speak with the healthcare provider who is ordering the blood tests for specific withholding instructions. The FDA is requesting information
about any adverse events or side effects you may experience related to the use of biotin or products containing biotin.