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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email to find out what information you need to submit for review.


Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Hematopoietic stem cell therapy (also known as bone marrow transplantation)

    Randomized study to test safety and effectiveness of bone marrow transplantation compared with standard treatment for active MS.
  2. Clinical Trial: High-dose cyclophosphamide

    Pilot study in aggressive MS
  3. Clinical Trial: Memory retraining

    This study examines the effects of a memory retraining technique. The study involves 2-3 hour test sessions (baseline, short-term follow up, long-term follow up) and training sessions (2 one-hour sessions a week for 5 weeks). There is a 50/50 chance of being in a treatment gr...
  4. Clinical Trial: Computerized Cognitive Exercise Training

    Comparing two different computer-based cognitive training programs in people with all types of MS and CIS in a 12-week study, to determine effects on compliance, performance on study tasks and neuropsychological measures, quality of life and functional status. Compensation...
  5. Clinical Trial: Idebenone (an antioxidant)

    Double-blinded, placebo-controlled clinical trial to determine the safety, effectiveness, and mechanism of action of idebenone in people with primary-progressive MS.
  6. Clinical Trial: Rituximab

    Researchers at the National Institutes of Health in Bethesda, Maryland are looking to recruit 80 people with secondary-progressive Multiple Sclerosis (secondary-progressive MS) to evaluate the safety and effectiveness of rituximab.  
  7. Clinical Trial: Non-impact aerobics for balance

    Testing whether non-impact aerobics can improve balance more significantly than a control intervention in people with relapsing-remitting MS.
  8. Clinical Trial: Estriol

    A double-blind, placebo controlled trial to determine whether estriol treatment (added on to standard therapies) improves cognition in women with multiple sclerosis.
  9. Clinical Trial: Vitamin D supplementation

    Comparing the effectiveness of the current recommended amount of vitamin D supplementation versus high dose vitamin D supplementation at reducing MS disease activity, when added to standard therapy with glatiramer acetate (Copaxone®, Teva Pharmaceutical Industries) in peop...
  10. Research Study: Differential Hippocampal Vulnerability as a Mechanism for Major Depression in MS

    To determine if similar patterns of brain changes are found in people with depression alone and people with depression in combination with MS to help target therapies to address depressive symptoms of MS.  


Learn About Clinical Trials

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