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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: High-dose cyclophosphamide

    Pilot study in aggressive MS
  2. Clinical Trial: Idebenone (an antioxidant)

    Double-blinded, placebo-controlled clinical trial to determine the safety, effectiveness, and mechanism of action of idebenone in people with primary-progressive MS.
  3. Clinical Trial: Estriol

    A double-blind, placebo controlled trial to determine whether estriol treatment (added on to standard therapies) improves cognition in women with multiple sclerosis.
  4. Clinical Trial: Vitamin D supplementation

    Comparing the effectiveness of the current recommended amount of vitamin D supplementation versus high dose vitamin D supplementation at reducing MS disease activity, when added to standard therapy with glatiramer acetate (Copaxone®, Teva Pharmaceutical Industries) in peop...
  5. Research Study: Generating Stem Cells for MS Research

    Investigators at The New York Stem Cell Foundation (NYSCF) Laboratory are recruiting 100 people with relapsing remitting, secondary progressive, and primary progressive forms of MS to undergo skin biopsies for the purposes of generating stem cell lines. 
  6. Research Study: Investigators Seeking Tissue Samples Previously Obtained from People with MS and Similar Diseases

    In order to discover the triggers of MS, National MS Society-funded investigators at the University of Utah are seeking to collect existing brain biopsy tissue from individuals nationwide who underwent a brain biopsy to diagnose an episode of “acute demyelinating disease,...
  7. Clinical Trial: Medical Food

    A placebo-controlled study to determine the potential benefits of a Medical Food on cognitive impairment in people with MS. Read more here .
  8. Research Study: Vitamin A & D

    A research study to compare the level of vitamin A in people with relapsing remitting and secondary progressive Multiple Sclerosis who have a normal vitamin D level or are supplemented with Vitamin D to get them to a normal level. Read more
  9. Clinical Trial: Warm and Cold Compress to Reduce Injection Site Erythema Due to Peginterferon-beta-1a in MS

    A pilot study of warm and cold compress to reduce injection site erythema due to peginterferon beta-1a in multiple sclerosis.
  10. Clinical Trial: Fingolimod

    The purpose of this world-wide prospective parallel-cohort study in patients with relapsing forms of MS, either newly treated with fingolimod or receiving another disease-modifying therapy, is to further explore the incidence of selected safety- related outcomes and to fur...

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