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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Warm and Cold Compress to Reduce Injection Site Erythema Due to Peginterferon-beta-1a in MS

    A pilot study of warm and cold compress to reduce injection site erythema due to peginterferon beta-1a in multiple sclerosis.
  2. Research Study: Vitamin A & D

    A research study to compare the level of vitamin A in people with relapsing remitting and secondary progressive Multiple Sclerosis who have a normal vitamin D level or are supplemented with Vitamin D to get them to a normal level. Read more
  3. Research Study: Generating Stem Cells for MS Research

    Investigators at The New York Stem Cell Foundation (NYSCF) Laboratory are recruiting 100 people with relapsing remitting, secondary progressive, and primary progressive forms of MS to undergo skin biopsies for the purposes of generating stem cell lines. 
  4. Clinical Trial: Plegridy™ (Peginterferon β-1a) Real World Effectiveness and Safety Observational Program

    The purpose of this observational study is to find out more about the long-term safety and effectiveness of Plegridy, over approximately a five-year time period. Information on side effects (for example, flu-like symptoms [FLS], injection site reactions [ISRs], and other serio...
  5. Ofatumumab Versus Teriflunomide

    To compare the efficacy and safety of ofatumumab administered subcutaneously (sc) every 4 weeks versus teriflunomide administered orally once daily in patients with relapsing multiple sclerosis.
  6. Clinical Trial: Keeogo™ (motorized walking assistive device)

    A study to assess the use of a wearable lower body device to help knee control while walking.
  7. Research Study: Investigators Seeking Tissue Samples Previously Obtained from People with MS and Similar Diseases

    In order to discover the triggers of MS, National MS Society-funded investigators at the University of Utah are seeking to collect existing brain biopsy tissue from individuals nationwide who underwent a brain biopsy to diagnose an episode of “acute demyelinating disease,” i...
  8. Clinical Trial: Gilenya (fingolimod)

    The purpose of this study is to monitor the safety of fingolimod and other disease-modifying treatments in patients with relapsing multiple sclerosis under conditions of routine medical practice   UPDATE 17 June 2016 The study has finished enrolling participants with med...
  9. Clinical Trial: Effect of Intermittent vs Continuous walking on gait kinematics in persons with MS

    Previous studies have shown that persons with MS have better gait endurance and less fatigue if they practice walking intermittently rather than continuously. The purpose of this study is to determine what is the difference in gait characteristics between intermittent and con...
  10. Clinical Trial: Complementary and Alternative Medicine Telerehabilitation Intervention

    The purpose of this study is to compare the effects of two delivery models of an evidence-based complementary alternative medicine (CAM) program that combines neurorehabilitative (functional) exercise, Yoga and Pilates for individuals with multiple sclerosis (MS).  CAM will be...

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