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Clinical Trial: Improving cognition in people with progressive MS

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Details
Type of MS: PPMS|SPMS
Treatment mode of action: To improve cognitive function
Number of Subjects: 40
Medication: cognitive rehabilitation and exercise
Location: Alabama|New Jersey|New York|Pennsylvania
Institutions: Please see below Contact Information
Please see below

Funding:

MS Society of Canada

Description

Please note: The study sites for this trial are in Birmingham, AL, and East Hanover, NJ. Participation will require travel to those locations.

Participants are people aged 25 to 65, with a diagnosis of progressive MS, who are not dependent on a wheelchair for mobility. Participants will receive compensation for participation.

The study examines the effects of combining cognitive rehabilitation and exercise as a form of intervention in the treatment of cognitive dysfunction in people with progressive MS. Participants are asked to come to the center for a baseline screening followed by intervention visits consisting of exercise and cognitive rehabilitation two times per week for a total of 24 testing sessions over 12 weeks. Upon completion of the intervention, participants return for a short term follow-up assessment, a long term follow-up assessment 6 months after completing the intervention, as well as a virtual follow-up to be completed one year and two years after completing the intervention. At the time of the baseline, short term and long term follow-up screenings, an optional MRI portion of the study is administered. Participants will complete a testing session during a fMRI scan.

Site Contact Information

Alabama
Petra Silic
Exercise Neuroscience Research Laboratory
Department of Physical Therapy
Community Health Services Bldg 19th, Suite 301
933 19th Street South, Birmingham, AL 35205
Phone: 205-975-1336 
Email: enrl@uabmc.edu

New Jersey
Blake Bichler
Kessler Foundation
Address: 120 Eagle Rock Ave. East Hanover, NJ 07936
Phone: 973-324-0828
Email: bbichler@kesslerfoundation.org

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