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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Cognitive Rehabilitation Combined with Eye Movements

    This study is looking at how 12 weeks of computer-based cognitive rehabilitation may help improve memory and attention.  Key study eligibility requirements: Right handed adults diagnosed with RRMS. No relapses in the past 6 months. Noticeable decline in memory or other...
  2. Clinical Trial: Arbaclofen extended release tablets

    Researchers are recruiting men with MS and spasticity to determine the effects of Arbaclofen extended release tablets on sperm.
  3. Clinical Trial: An online program to reduce depression

    SUMMARY: Investigators at three sites in the United States and two sites in Germany are recruiting 400 people with all forms of MS for a study testing the effectiveness of a computer training program for overcoming MS-related depression. The lead investigator is Stefan Gold, P...
  4. Clinical Trial: H.P. Acthar Gel®

    Investigators are recruiting 66 people with relapsing-remitting MS who have had a relapse and did not experience recovery from the relapse after high-dose intravenous or oral steroids. This study aims to determine the safety and effectiveness of H.P. Acthar Gel® (repository co...
  5. Clinical Trial: Suvorexant for Fatigue and Insomnia

    The MS Center at EvergreenHealth is conducting a randomized, double-blind, placebo-controlled, cross-over trial to assess the safety, tolerability, and efficacy of suvorexant (Belsomra®) in treating insomnia in adults with multiple sclerosis (MS) and fatigue. This study will a...
  6. Clinical Trial: Immune Phenotype Biomarkers After Treatment With Fingolimod

    The MS Center at EvergreenHealth is conducting a study of immune phenotype biomarkers in patients with Relapsing Multiple Sclerosis (RMS) after treatment with 0.5mg fingolimod. This study uses a two-cohort, nonrandomized, open-label, multicenter design. The study consists of t...
  7. Clinical Trial: A Low-Fat Diet for Fatigue in MS

    Dr. Vijayshree Yadav, a neurologist at Oregon Health & Science University, is conducting a study to see if following a low fat diet can help decrease fatigue in people with multiple sclerosis. We are looking for individuals 18-70 years old who are not already following a low-f...
  8. Clinical Trial: Treatment Strategies to Prevent Disability

    A study based at Johns Hopkins University is comparing two treatment strategies in 900 people newly diagnosed, or with onset/diagnosis in the past who have received minimal or no treatment, with the relapsing-remitting form of MS. The study is recruiting at approximately 45 ce...
  9. Clinical Trial: Opicinumab (BIIB033)

    The objective of this study is to evaluate the efficacy and safety of BIIB033 used as add-on therapy to anti-inflammatory disease-modifying therapies (DMTs) in subjects with relapsing multiple sclerosis (RMS). BIIB033 is human monoclonal antibody directed against the LINGO-1 p...
  10. Clinical Trial: Gaze and postural stability in persons with MS

    The objective of the study is to understand vision and balance stability and prevent falls in clinical populations. We want to understand how people stabilize their vision and posture during head and body movement and how treatment (exercise based training) may improve these s...
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