Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

NARCOMS Patient Registry

Register as a willing MS research participant to facilitate multicenter studies. Initiated by the Consortium of MS Centers.

Visit NARCOMS

Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

Research Study: Mechanisms of Low Physical Work Capacity, Fatigue, and Reduced Mobility

You are being asked to be a subject in a research study about blood flow regulation during exercise and how that may affect work capacity (the ability to perform exercise). This study will examine cardiac output (how much blood your heart can pump each minute) during a treadmi...

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Clinical Trial: Immune responses to COVID vaccines in people with MS on ocrelizumab

It is not know whether people receiving ocrelizumab for MS mount adequate immune responses to COVID-19 vaccine. The study is designed to investigate B-cell and T-cell responses to COVID-19 vaccination in patients treated with Ocrevus. There are 5 visits for this study. All...

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Clinical Trial: Ofatumumab for Patients with Relapsing Multiple Sclerosis

MS study evaluating the continued effectiveness, safety and tolerability of Ofatumumab in adults, between the ages 18-60, with relapsing multiple sclerosis who are transitioning from traditional anti-CD20 therapy. Click on this link to answer a few questions to see if you q...

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Clinical Trial: Ozanimod to Improve Cognitive Function

Investigators are recruiting 250 people with relapsing forms of MS for a clinical trial to determine if ozanimod (Zeposia ® , Bristol Myers Squibb) improves cognitive functions, specifically information processing speed. The study is funded by Celgene. Read more

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Clinical Trial: Ofatumumab

MS study to evaluate the effectiveness of ofatumumab after transitioning from oral therapy, in adults 18 to 60 with relapsing MS experiencing breakthrough disease. Study participation includes in-person visits, blood draws, MRI appointments, and use of electronic devices and ...

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Clinical Trial: Higher dose of ocrelizumab in PPMS

An open-label, single-arm study to evaluate the effectiveness and safety of ocrelizumab in people with primary progressive MS. Subjects participating in the study will complete the following procedures: study visits, blood draw/sample collections, MRI Scans, potential lumbar p...

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Clinical Trial: Higher dose of ocrelizumab in PPMS

An open-label, single-arm study to evaluate the effectiveness and safety of ocrelizumab in people with primary progressive MS. Subjects participating in the study will complete the following procedures: study visits, blood draw/sample collections, MRI Scans, potential lumbar p...

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Clinical Trial: Ozanimod for Cognitive Function

This is a multicenter, single-arm, open-label study to describe the change from baseline in cognitive processing speed in subjects with relapsing multiple sclerosis (RMS) treated with ozanimod HCl 1 mg at 3 years. All enrolled subjects will receive orally administered ozanimod...

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Clinical Trial: Treadmill training to reduce falls

Falls present a serious challenge facing individuals affected by multiple sclerosis. This study aims to examine if and to what extent slip-based training can reduce the risk of falls for people with multiple sclerosis. The researchers are seeking adults (18-65 years old) with ...

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Clinical Trial: Employment-Related Telephone Intervention for Pain Study (E-TIPS)

The E-TIPS trial will evaluate an evidence-based, telehealth pain self-management intervention compared to standard care (a waitlist) for chronic pain in adults with multiple sclerosis who are employed. Participants from anywhere in the US will be randomly assigned to either E...

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Participate in a Clinical Trial

Clinical Trials in MS

NARCOMS Patient Registry

Posting a Trial

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Clinical Trials In Your Area

Research Study: Mechanisms of Low Physical Work Capacity, Fatigue, and Reduced Mobility

Clinical Trial: Immune responses to COVID vaccines in people with MS on ocrelizumab

Clinical Trial: Ofatumumab for Patients with Relapsing Multiple Sclerosis

Clinical Trial: Ozanimod to Improve Cognitive Function

Clinical Trial: Ofatumumab

Clinical Trial: Higher dose of ocrelizumab in PPMS

Clinical Trial: Higher dose of ocrelizumab in PPMS

Clinical Trial: Ozanimod for Cognitive Function

Clinical Trial: Treadmill training to reduce falls

Clinical Trial: Employment-Related Telephone Intervention for Pain Study (E-TIPS)

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The National MS Society is Here to Help

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