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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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NOTE: The COVID-19 pandemic may affect the status of the studies listed on this website. Trial recruitment or visits may be postponed, and responses from study coordinators may be delayed. If you are enrolled in a study, your study coordinator will likely reach out to you with any changes. Learn what you need to know about COVID-19

Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Virtual Reality for MS

    Researchers are looking at the impact of virtual reality on walking for individuals with relapse and remitting Multiple Sclerosis. The intervention group will receive 18 sessions of Treadmill Training with Virtual Reality and the active control comparison will receive 18 tr...
  2. Clinical Trial: Tracking Health in Multiple Sclerosis (TracMS)

    In Trac-MS researchers are interested in learning more about the relationship between everyday behaviors, thinking abilities, and brain health in people with relapsing-remitting multiple sclerosis and cognitive impairment, ages 30-59. Specifically, they are interested in exami...
  3. Clinical Trial: Siponimod in advancing forms of relapsing MS

    Exploring the safety and tolerability of conversion from oral or injectable disease modifying therapies to dose-titrated Oral Siponimod in patients with advancing forms of relapsing multiple sclerosis. You, or someone you care for, may be able to take part if you/they: • are...
  4. Clinical Trial: Effects of epidural and transcutaneous spinal stimulation

    Investigators are recruiting individuals with MS for a research study to compare the effects of epidural (invasive) and transcutaneous (non-invasive) spinal stimulation approaches to improve mobility. Participants will first undergo up to 3 experimental sessions with transcuta...
  5. Clinical Trial: Tai Chi and Mindfulness Training

    Investigators are recruiting people with all subtypes of MS (participants need to capable of standing and moving unaided for a minimum of 15 minutes at a time) to investigate the impact of mindfulness training on balance and wellbeing in individuals with MS. This is a communit...
  6. Clinical Trial: Behavioral Intervention for Physical Activity in Multiple Sclerosis

    The Exercise Neuroscience Research Laboratory at the University of Alabama at Birmingham are currently recruiting for a National MS Society funded research study to compare two behavioral interventions on modifying and self-regulating health behaviors in people who have MS. Pa...
  7. Clinical Trial: Gut bacteria and MS

    The Yale-Griffin Prevention Research Center, the Multiple Sclerosis Treatment Center at Griffin Hospital, and Yale University are teaming up to study whether changing the bacteria in the gut can affect the process that leads to the development of multiple sclerosis (MS). This ...
  8. Clinical Trial: Virtual Reality to Improve Quality of Life

    Participants with MS and other neurological disorders will be recruited to complete sessions of virtual reality (VR) viewing and game playing. VR has been shown to have therapeutic benefit in certain patient populations and requires further clinical study to determine the exte...
  9. Clinical Trial: positive airway pressure therapy

    A randomized trial of positive airway pressure therapy to treat cognitive dysfunction in people with MS and obstructive sleep apnea. Read more here .
  10. Research Study: MS Biomarkers

    The Sutter Health MS genetic study is recruiting people with MS from ten sites across its healthcare system to participate in a DNA sequencing study. The main objectives are to identify biomarkers of disease subtype, progression, and treatment response. The study is open to cu...
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