Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

NARCOMS Patient Registry

Register as a willing MS research participant to facilitate multicenter studies. Initiated by the Consortium of MS Centers.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

Clinical Trial: Immune responses to COVID vaccines in people with MS on ocrelizumab

It is not know whether people receiving ocrelizumab for MS mount adequate immune responses to COVID-19 vaccine. The study is designed to investigate B-cell and T-cell responses to COVID-19 vaccination in patients treated with Ocrevus. There are 5 visits for this study. All...

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Clinical Trial: Ofatumumab for Patients with Relapsing Multiple Sclerosis

MS study evaluating the continued effectiveness, safety and tolerability of Ofatumumab in adults, between the ages 18-60, with relapsing multiple sclerosis who are transitioning from traditional anti-CD20 therapy. Click on this link to answer a few questions to see if you q...

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Clinical Trial: Ozanimod to Improve Cognitive Function

Investigators are recruiting 250 people with relapsing forms of MS for a clinical trial to determine if ozanimod (Zeposia ® , Bristol Myers Squibb) improves cognitive functions, specifically information processing speed. The study is funded by Celgene. Read more

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Clinical Trial: Enhancing Energy in MS (ENERGY Study)

People with multiple sclerosis (MS) often have problems with fatigue. For some people, fatigue is their most debilitating symptom of MS. Yet, many of the available treatments provide inadequate relief for fatigue. Past research has found that training in self-hypnosis is linke...

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Clinical Trial: Ofatumumab

MS study to evaluate the effectiveness of ofatumumab after transitioning from oral therapy, in adults 18 to 60 with relapsing MS experiencing breakthrough disease. Study participation includes in-person visits, blood draws, MRI appointments, and use of electronic devices and ...

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Clinical Trial: ReCOVER – Clemastine Fumarate in Optic Neuritis

WE ARE ACTIVELY RECRUITING PEOPLE EXPERIENCING A SUSPECTED OR DIAGNOSED ACUTE OPTIC NEURITIS IN A PREVIOUSLY UNAFFECTED EYE. VISUAL SYMPTOMS MUST BE WITHIN THE PAST 3 WEEKS AND THE PATIENT MUST BE STEROID NAIVE. ReCOVER aims to assess the effect of Clemastine Fumarate as a...

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Clinical Trial: Higher dose of ocrelizumab in PPMS

An open-label, single-arm study to evaluate the effectiveness and safety of ocrelizumab in people with primary progressive MS. Subjects participating in the study will complete the following procedures: study visits, blood draw/sample collections, MRI Scans, potential lumbar p...

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Clinical Trial: Higher dose of ocrelizumab in PPMS

An open-label, single-arm study to evaluate the effectiveness and safety of ocrelizumab in people with primary progressive MS. Subjects participating in the study will complete the following procedures: study visits, blood draw/sample collections, MRI Scans, potential lumbar p...

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Clinical Trial: Evaluating Mobility Interventions in the Real World

What is this study about? We want to study the best ways to help people walk and run better using lower-limb orthoses (leg braces). To do this, we will study people who use orthoses, as well as people who don’t. What will happen during the study? You might do an...

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Clinical Trial: IMS001 in people with MS

The purpose of this research is to determine the safety, tolerability, efficacy, and optimal dose regimen of an investigational human embryonic stem cell derived (hESC) mesenchymal stem cell (MSC) product to treat MS called IMS001.Taking part in this research will last for up ...

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Participate in a Clinical Trial

Clinical Trials in MS

NARCOMS Patient Registry

Posting a Trial

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Clinical Trials In Your Area

Clinical Trial: Immune responses to COVID vaccines in people with MS on ocrelizumab

Clinical Trial: Ofatumumab for Patients with Relapsing Multiple Sclerosis

Clinical Trial: Ozanimod to Improve Cognitive Function

Clinical Trial: Enhancing Energy in MS (ENERGY Study)

Clinical Trial: Ofatumumab

Clinical Trial: ReCOVER – Clemastine Fumarate in Optic Neuritis

Clinical Trial: Higher dose of ocrelizumab in PPMS

Clinical Trial: Higher dose of ocrelizumab in PPMS

Clinical Trial: Evaluating Mobility Interventions in the Real World

Clinical Trial: IMS001 in people with MS

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