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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Ofatumumab versus Teriflunomide

    A randomized, double-blind, double-dummy, parallel-group study comparing the efficacy and safety of ofatumumab versus teriflunomide in patients with relapsing multiple sclerosis.

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  2. Clinical Trial: Ofatumumab versus Teriflunomide

    A randomized, double-blind, double-dummy, parallel-group study comparing the efficacy and safety of ofatumumab versus teriflunomide in patients with relapsing multiple sclerosis.

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  3. Clinical Trial: Ocrelizumab

    An open-label, single-arm study to evaluate the effectiveness and safety of ocrelizumab in patients with early stage relapsing remitting multiple sclerosis.

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  4. Clinical Trial: N-Acetyl Cysteine

    The study consists of two arms. The first arm of this study will receive intravenous and oral NAC, a strong antioxidant that increases brain glutathione. NAC, is the N-acetyl derivative of the naturally occurring amino acid, L-cysteine. It has the potential to increase glutath...

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  5. Clinical Trial: Mindfulness Meditation

    This study will compare standard sleep hygiene techniques versus a nine-week, sleep-based mindfulness meditation course for the treatment of chronic insomnia in Multiple Sclerosis. Outcome measures will include a subjective and object measures of sleep. A number of questionnai...

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  6. Clinical Trial: Methylphenidate

    This study examines the use of methylphenidate for persons with MS. This medication has been used to treat cognition, attention and fatigue in other neurological conditions such as Parkinson’s and traumatic brain injury. Kessler Foundation researchers want to see if this medic...

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  7. Clinical Trial: MEDI-551 in NMO

    Local doctors are studying an investigational medication.  Qualified volunteers will receive at no cost: Study medication Study-related care from a local doctor Compensation for travel.    If you are at least 18 years old and have Neuromyelitis Optica (NMO) or a Neuro...

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  8. Clinical Trial: Light Therapy for MS-related fatigue

     Randomized research study to investigate if light therapy can be a potential treatment option for MS-related fatigue. The study involves 4  1-hour visits over 10 weeks. During the study period you will be asked to track sleep and fatigue levels daily (<5 minutes/day), and for...

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  9. Clinical Trial: Leg strength asymmetries, mobility, and fatigue

    The goal of this study is to determine the association of differences in leg strength between the more and less affected side and walking performance and characteristics. The study involves two sessions (each 90-120 minutes) during which we will perform strength testing, a 6-m...

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  10. Clinical Trial: iQool My MS

    A double-blind, placebo controlled trial to determine the effect of a tissue-selective estrogen modulator (TSEC) on tolerability and menopausal symptoms in perimenopasual women with multiple sclerosis. Study Site UCSF Medical Center, San Francisco, CA

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