Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

NARCOMS Patient Registry

Register as a willing MS research participant to facilitate multicenter studies. Initiated by the Consortium of MS Centers.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

Research Study: cognitive testing for MS

Researchers are currently enrolling participants in a study of cognitive testing for Multiple Sclerosis. This study compares computerized and in-person cognitive testing, to see how well the results match. Participants will complete assessments of sensory, motor, and cognitive...

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Clinical Trial: Siponimod in MS

To assess early phase safety and tolerability of converting from approved oral and injectable disease-modifying therapies for relapsing MS to siponimod. The results of this study will guide clinically relevant decisions related to the transition from frequently used therapies ...

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Research Study: Assessment of Portable Magnetic Resonance Imaging

This study aims to examine the use of a novel portable MRI machine, which has been developed by physicists and physicians at the Massachusetts General Hospital. The MRI machine uses permanent magnets, meaning it doesn’t need liquid helium coolant, makes significantly less sou...

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Clinical Trial: Malignancies and MS Treatment

VERISMO is a long-term, observational safety study of patients who are newly starting Ocrevus, or Lemtrada, Mavenclad, Tecfidera, Gilenya, Tysabri, or Aubagio. The goal of the study is to determine the full safety profile of Ocrevus compared to these other MS DMTs (disease mod...

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Clinical Trial: Cognitive Processing Speed Changes in Relapsing MS Treated With Ozanimod (RPC-1063)

A study to determine if oral ozanimod can affect cognitive processing speed in people with relapsing MS. All subjects will receive orally administered ozanimod HCl 1 mg. Please note: In response to the recent developments of the COVID-19 pandemic, sites are implementing me...

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Clinical Trial: SAR442168

This is a Phase 3, randomized, double-blind, 2-arm, placebo-controlled, parallel-group, multicenter, trial to determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis

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Clinical Trial: SAR442168

A Phase 3, randomized, double-blind, efficacy and safety study comparing SAR442168 to placebo in participants with nonrelapsing secondary progressive multiple sclerosis (HERCULES)

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Research Study: Fatigue

Please note: This is not a clinical trial of an intervention, but rather a research study. The purpose of this study is to systematically evaluate the relationship between fatigue severity, autonomic (involuntary) symptom burden, and autonomic physiological markers in MS p...

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Clinical Trial: Cognitive Processing Speed Changes in Relapsing MS Treated With Ozanimod (RPC-1063)

A study to determine if oral ozanimod can affect cognitive processing speed in people with relapsing MS. All subjects will receive orally administered ozanimod HCl 1 mg. Please note: In response to the recent developments of the COVID-19 pandemic, sites are implementing me...

Get Details
Clinical Trial: STEP for MS, an Exercise Intervention

New research shows that exercise is good for people with MS and may decrease symptoms and improve health and walking ability. An exercise study called STEP for MS will compare the outcomes of a 16-week exercise program conducted at home to a program conducted in a gym. A train...

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Participate in a Clinical Trial

Clinical Trials in MS

NARCOMS Patient Registry

Posting a Trial

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Clinical Trials In Your Area

Research Study: cognitive testing for MS

Clinical Trial: Siponimod in MS

Research Study: Assessment of Portable Magnetic Resonance Imaging

Clinical Trial: Malignancies and MS Treatment

Clinical Trial: Cognitive Processing Speed Changes in Relapsing MS Treated With Ozanimod (RPC-1063)

Clinical Trial: SAR442168