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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: GET (Graduated Exercise Training) Smart Study

    The GET Smart study is looking at whether exercise has an impact on cognition in people with MS. Researchers at the University of Washington are studying exercise because other studies have shown that exercise can help cognition in other non-MS populations. However, curren...

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  2. Clinical Trial: Fingolimod

    Patients with relapsing forms of multiple sclerosis either newly treated with fingolimod or treated with another approved disease-modifying therapy and switched to fingolimod.

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  3. Clinical Trial: Keeogo Powered Dermoskeleton

    Open-label, comparative, randomized, cross-over, safety and efficacy study of the Keeogo powered dermoskeleton as an ambulation aid in individuals with walking disabilities.

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  4. Clinical Trial: Water aerobics intervention

    This study will provide key insight into: 1) the immediate impact and durability of a one-week moderate intensity water aerobics intervention on cognition in this population, 2) the potential contribution of cerebral perfusion and fitness to cognitive changes, and 3) any p...

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  5. Clinical Trial: Keeogo™ (motorized walking assistive device)

    A study to assess the use of a wearable lower body device to help knee control while walking.

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  6. Clinical Trial: Exercise Training

    The study examines how brain function is improved by exercise. The study involves paper tests, fitness tests and an MRI scan (two sessions: baseline and follow-up), four group exercise classes at Kessler Foundation (one hour each), an individualized at-home exercise program (3...

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  7. Clinical Trial: Methylphenidate

    This study examines the use of methylphenidate for persons with MS. This medication has been used to treat cognition, attention and fatigue in other neurological conditions such as Parkinson’s and traumatic brain injury. Kessler Foundation researchers want to see if this medic...

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  8. Clinical Trial: Speed of Processing Training

    This study examines a technique to improve the time it takes to process information in people with MS. The study involves 2-3 hour test sessions (baseline, short-term follow up, long-term follow up) and a training program (2 one-hour sessions a week, 5 weeks). There is a 50/50...

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  9. Clinical Trial: Plegridy™ (Peginterferon β-1a) Real World Effectiveness and Safety Observational Program

    The purpose of this observational study is to find out more about the long-term safety and effectiveness of Plegridy, over approximately a five-year time period. Information on side effects (for example, flu-like symptoms [FLS], injection site reactions [ISRs], and other serio...

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  10. Clinical Trial: Medication Satisfaction with Copaxone

    The purpose of this study is to compare patient medication satisfaction between the Copaxone 40 mg/mL three time a week (TIW) group and the Copaxone 20 mg/mL once daily (QD) groups. After 6 months of either treatment assignment, all subjects will enter the 6 month extension ph...

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