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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email to find out what information you need to submit for review.


Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Diet for MS Symptoms

    The purpose of this study is to determine if a high quality diet (with low glycemic load) has an impact on MS symptoms such as pain and fatigue in people with MS ages 18-65, MS clinical outcomes such as hand/leg function and cognition, and risk for comorbidities (e.g. diabe...
  2. Research Study: Role of the Gut Microbiome in Depression in MS

    Investigators at Washington University in St. Louis are conducting a research study for people with multiple sclerosis (MS). The purpose of this study is to determine the potential effects of the gut microbiome on depression in MS. They are enrolling individuals with MS (inclu...
  3. Research Study: How Body Mass Composition Impacts Pediatric MS

    Study Description: MS researchers at the University of Virginia (UVA) & Children’s Hospital of Philadelphia (CHOP) seeks children, adolescents and young adults diagnosed with Pediatric-Onset Multiple Sclerosis within the past 3 years, and people without MS who are between ...
  4. Research Study: Portable MRI

    Researchers at the Massachusetts General Hospital are studying a portable MRI machine. Most MRI machines are extremely large, cost millions of dollars, and require specialized and expensive equipment to function. This portable MRI machine costs less than a traditional machine,...
  5. Research Study: Close Relatives of People with MS

    Researchers at Yale University are looking for close family members of people with MS to help them discover the earliest immune system changes that ultimately lead to Multiple Sclerosis (MS). Who can participate? Close relatives (parent, sibling, child) of someone with MS ...
  6. Research Study: MS and Aging

    Purpose of the study The goal of this research study is to evaluate how the brain is involved in walking in older adults with and without MS. The results will provide valuable new information about how brain structure and function affect the affect walking abilities and ri...
  7. Research Study: Research Study for Individuals Planning to Become Pregnant with MS

    Researchers at Project Clio in Boston are recruiting individuals with MS that are planning to become pregnant for our Project Clio TCR: Pathfinder study. If you live in the New England area, have MS and plan to become pregnant soon, you qualify for our study. The goal of this ...
  8. Clinical Trial: Effects of Feedback Presentation on Fatigue and Learning on Fatigue and Learning

    Researchers at Kessler Foundation are interested in learning whether different types of feedback (assessments of one’s performance on a task) might lessen fatigue in MS. Participants will complete pen and paper tests (4 hours) then complete a multiple-choice task during an MRI...
  9. Clinical Trial: Treadmill Walking and Anxiety in Persons with MS

    Anxiety is common in MS, yet we know very little about how it can be managed. This study examines the effect of a single bout of moderate-intensity aerobic exercise on state anxiety in persons with MS who have elevated anxiety levels indicative of generalized anxiety disorder ...
  10. Clinical Trial: Gut bacteria and MS

    The Yale-Griffin Prevention Research Center, the Multiple Sclerosis Treatment Center at Griffin Hospital, and Yale University are teaming up to study whether changing the bacteria in the gut can affect the process that leads to the development of multiple sclerosis (MS). This ...
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