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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Keeogo Powered Dermoskeleton

    Open-label, comparative, randomized, cross-over, safety and efficacy study of the Keeogo powered dermoskeleton as an ambulation aid in individuals with walking disabilities.
  2. Clinical Trial: iQool My MS

    A double-blind, placebo controlled trial to determine the effect of a tissue-selective estrogen modulator (TSEC) on tolerability and menopausal symptoms in perimenopasual women with multiple sclerosis. Study Site UCSF Medical Center, San Francisco, CA
  3. Clinical Trial: Idebenone (an antioxidant)

    Double-blinded, placebo-controlled clinical trial to determine the safety, effectiveness, and mechanism of action of idebenone in people with primary-progressive MS.
  4. Clinical Trial: High-dose cyclophosphamide

    Pilot study in aggressive MS
  5. Clinical Trial: High-Dose Biotin (MD1003)

    Investigators worldwide are conducting a clinical trial testing high-dose biotin (MD1003, MedDay Pharmaceuticals SA) versus inactive placebo in 600 people with secondary or primary progressive MS. Participants can remain on existing disease-modifying treatments (such as ocreli...
  6. Clinical Trial: Fingolimod

    Patients with relapsing forms of multiple sclerosis either newly treated with fingolimod or treated with another approved disease-modifying therapy and switched to fingolimod.
  7. Clinical Trial: Fingolimod

    The purpose of this world-wide prospective parallel-cohort study in patients with relapsing forms of MS, either newly treated with fingolimod or receiving another disease-modifying therapy, is to further explore the incidence of selected safety- related outcomes and to fur...
  8. Clinical Trial: Exercise Training

    The study examines how brain function is improved by exercise. The study involves paper tests, fitness tests and an MRI scan (two sessions: baseline and follow-up), four group exercise classes at Kessler Foundation (one hour each), an individualized at-home exercise program (3...
  9. Clinical Trial: Estriol

    A double-blind, placebo controlled trial to determine whether estriol treatment (added on to standard therapies) improves cognition in women with multiple sclerosis.
  10. Clinical Trial: Effect of Maximal Strength training on Gait and balance in persons with MS

    Subjects will undergo weight training using relatively high weights and low repetitions to determine the effect of this type of training on gait endurance, balance, and fatigue.

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