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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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NOTE: The COVID-19 pandemic may affect the status of the studies listed on this website. Trial recruitment or visits may be postponed, and responses from study coordinators may be delayed. If you are enrolled in a study, your study coordinator will likely reach out to you with any changes. Learn what you need to know about COVID-19

Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Tai Chi and Mindfulness Training

    Investigators are recruiting people with all subtypes of MS (participants need to capable of standing and moving unaided for a minimum of 15 minutes at a time) to investigate the impact of mindfulness training on balance and wellbeing in individuals with MS. This is a communit...
  2. Clinical Trial: Behavioral Intervention for Physical Activity in Multiple Sclerosis

    The Exercise Neuroscience Research Laboratory at the University of Alabama at Birmingham are currently recruiting for a National MS Society funded research study to compare two behavioral interventions on modifying and self-regulating health behaviors in people who have MS. Pa...
  3. Clinical Trial: Siponimod in Advancing Relapsing MS

    The main reason for you to take part in this study is to examine how safe and tolerable Siponimod 2mg is in patients with advancing RMS who are switching from the RMS medicine they are currently taking to Siponimod.
  4. Clinical Trial: ReWRAP: Remyelination for Women at Risk for Axonal Loss and Progression

    Dr. Riley Bove and her colleagues at the UCSF Multiple Sclerosis center are conducting a clinical trial to assess the efficacy of bazedoxifene (BZA) in promoting the repair of myelin (remyelination), an important insulating layer for neurons in the central nervous system a...
  5. Clinical Trial: Gut bacteria and MS

    The Yale-Griffin Prevention Research Center, the Multiple Sclerosis Treatment Center at Griffin Hospital, and Yale University are teaming up to study whether changing the bacteria in the gut can affect the process that leads to the development of multiple sclerosis (MS). This ...
  6. Clinical Trial: MBCT and CBT for Chronic Pain in Multiple Sclerosis

    Chronic pain is a disabling and persistent symptom associated with MS, and it has been linked with poorer health, depression, sleep disruption, inactivity, and problems with work and social life. Currently, drugs used to treat pain rarely provide complete relief and often invo...
  7. Clinical Trials: Transcranial Direct Current Stimulation Studies

    Researchers at New York University are recruiting people with MS for three studies involving transcranial direct current stimulation (tDCS, which involves low electrical current delivered via electrodes). Clinical Trial: A Pilot Trial of Remotely-Supervised Transcranial Dire...
  8. Clinical Trial: Virtual Reality to Improve Quality of Life

    Participants with MS and other neurological disorders will be recruited to complete sessions of virtual reality (VR) viewing and game playing. VR has been shown to have therapeutic benefit in certain patient populations and requires further clinical study to determine the exte...
  9. Clinical Trial: positive airway pressure therapy

    A randomized trial of positive airway pressure therapy to treat cognitive dysfunction in people with MS and obstructive sleep apnea. Read more here .
  10. Clinical Trial: Bladder Study

    Difficulty in bladder emptying is a costly urinary condition that leads to urinary tract infections/stones, infection, bladder loss, and permanent kidney damage. Current therapies include bladder catheters or intermittent self-catheterization. Catheterization is a burden espec...
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