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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: MEDI-551 in NMO

    Local doctors are studying an investigational medication.  Qualified volunteers will receive at no cost: Study medication Study-related care from a local doctor Compensation for travel.    If you are at least 18 years old and have Neuromyelitis Optica (NMO) or a Neuro...
  2. Clinical Trial: Light Therapy for MS-related fatigue

     Randomized research study to investigate if light therapy can be a potential treatment option for MS-related fatigue. The study involves 4  1-hour visits over 10 weeks. During the study period you will be asked to track sleep and fatigue levels daily (<5 minutes/day), and for...
  3. Clinical Trial: Leg strength asymmetries, mobility, and fatigue

    The goal of this study is to determine the association of differences in leg strength between the more and less affected side and walking performance and characteristics. The study involves two sessions (each 90-120 minutes) during which we will perform strength testing, a 6-m...
  4. Clinical Trial: Keeogo Powered Dermoskeleton

    Open-label, comparative, randomized, cross-over, safety and efficacy study of the Keeogo powered dermoskeleton as an ambulation aid in individuals with walking disabilities.
  5. Clinical Trial: iQool My MS

    A double-blind, placebo controlled trial to determine the effect of a tissue-selective estrogen modulator (TSEC) on tolerability and menopausal symptoms in perimenopasual women with multiple sclerosis. Study Site UCSF Medical Center, San Francisco, CA
  6. Clinical Trial: Idebenone (an antioxidant)

    Double-blinded, placebo-controlled clinical trial to determine the safety, effectiveness, and mechanism of action of idebenone in people with primary-progressive MS.
  7. Clinical Trial: H.P. Acthar Gel®

    Investigators are recruiting 66 people with relapsing-remitting MS who have had a relapse and did not experience recovery from the relapse after high-dose intravenous or oral steroids. This study aims to determine the safety and effectiveness of H.P. Acthar Gel® (repository co...
  8. Clinical Trial: High-dose cyclophosphamide

    Pilot study in aggressive MS
  9. Clinical Trial: High-Dose Biotin (MD1003)

    Investigators worldwide are conducting a clinical trial testing high-dose biotin (MD1003, MedDay Pharmaceuticals SA) versus inactive placebo in 600 people with secondary or primary progressive MS. Participants can remain on existing disease-modifying treatments (such as ocreli...
  10. Clinical Trial: GET (Graduated Exercise Training) Smart Study

    The GET Smart study is looking at whether exercise has an impact on cognition in people with MS. Researchers at the University of Washington are studying exercise because other studies have shown that exercise can help cognition in other non-MS populations. However, curren...

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