Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

NARCOMS Patient Registry

Register as a willing MS research participant to facilitate multicenter studies. Initiated by the Consortium of MS Centers.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

Clinical Trial: Cognitive Processing Speed Changes in Relapsing MS Treated With Ozanimod (RPC-1063)

A study to determine if oral ozanimod can affect cognitive processing speed in people with relapsing MS. All subjects will receive orally administered ozanimod HCl 1 mg.

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Research Study: Physiologic dysfunction in MS-related Fatigue

This research study is designed to assess whether physiologic dysfunction contributes to fatigue in people with MS. This connection will help guide routine neurological treatment fatigue in MS in the future. Physiologic testing includes measurement of a person’s pupil functi...

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Clinical Trial: Robotic exoskeleton

The purpose of this research study is to evaluate the usefulness of a wearable robotic exoskeleton (RE) device, called Ekso-GT, to improve learning, memory and walking ability in persons with walking disability due to Multiple Sclerosis. The study will evaluate the mobility, l...

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Clinical Trial: Ocrelizumab

This is a double blind, multicenter study to evaluate the effectiveness, safety and pharmacokinetics (how the drug moves within the body) of a higher dose of ocrelizumab taken via intravenous infusion every 24 weeks in people with relapsing MS, in comparison to the approved 60...

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Clinical Trial: Estriol

A double-blind, placebo controlled trial to determine whether estriol treatment (added on to standard therapies) improves cognition in women with multiple sclerosis.

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Clinical Trial: Ozanimod for Cognitive Function

This is a multicenter, single-arm, open-label study to describe the change from baseline in cognitive processing speed in subjects with relapsing multiple sclerosis (RMS) treated with ozanimod HCl 1 mg at 3 years. All enrolled subjects will receive orally administered ozanimod...

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Clinical Trial: Lipoic acid for Treatment of Progressive Multiple Sclerosis (LAPMS)

Dr. Rebecca Spain, a neurologist at the VA Portland Health Care System, is conducting a multicenter study to see if the over the counter antioxidant, lipoic acid, helps multiple sclerosis (MS) and is safe to take in people with progressive forms of MS. They are looking for in...

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Research Study: Mechanisms of Low Physical Work Capacity, Fatigue, and Reduced Mobility

You are being asked to be a subject in a research study about blood flow regulation during exercise and how that may affect work capacity (the ability to perform exercise). This study will examine cardiac output (how much blood your heart can pump each minute) during a treadmi...

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Clinical Trial: Effect of Disease Modifying Therapy on Antibody Response to COVID-19 Vaccination in People with MS

The objective of the study is to determine whether certain disease modifying therapies impair or shorten immune responses to COVID-19 vaccines. The researchers are measuring antibody levels following vaccination with Moderna mRNA-1273 vaccine in people with MS. Therapies under...

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Clinical Trial: UCSF MS and COVID-19 Immunity Study

MS treatment involves the use of medications that target the immune system, which can increase the risk of certain infections. This study is being conducted to get a better understanding of how immunity to COVID-19 vaccination may be impacted by MS treatments. Criteria fo...

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Participate in a Clinical Trial

Clinical Trials in MS

NARCOMS Patient Registry

Posting a Trial

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Clinical Trials In Your Area

Clinical Trial: Cognitive Processing Speed Changes in Relapsing MS Treated With Ozanimod (RPC-1063)

Research Study: Physiologic dysfunction in MS-related Fatigue

Clinical Trial: Robotic exoskeleton

Clinical Trial: Ocrelizumab

Clinical Trial: Estriol

Clinical Trial: Ozanimod for Cognitive Function

Clinical Trial: Lipoic acid for Treatment of Progressive Multiple Sclerosis (LAPMS)

Research Study: Mechanisms of Low Physical Work Capacity, Fatigue, and Reduced Mobility

Clinical Trial: Effect of Disease Modifying Therapy on Antibody Response to COVID-19 Vaccination in People with MS

Clinical Trial: UCSF MS and COVID-19 Immunity Study

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The National MS Society is Here to Help

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