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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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NOTE: The COVID-19 pandemic may affect the status of the studies listed on this website. Trial recruitment or visits may be postponed, and responses from study coordinators may be delayed. If you are enrolled in a study, your study coordinator will likely reach out to you with any changes. Learn what you need to know about COVID-19

Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Back on Track to Healthy Living Study

    Chronic pain is a common and costly condition affecting millions of Americans. Chronic pain is also one of the most common symptoms associated with MS . Different types of treatment such as mindfulness meditation, cognitive therapy, and activation skills have been used to tre...
  2. Clinical Trial: Pathological Basis of MRI Signal Changes in Multiple Sclerosis

    Multiple sclerosis (MS) is a disease that damages the central nervous system (brain and spinal cord). This leads to increased physical disability over time. The disease is lifelong once it begins. Researchers want to learn more about the stages of multiple sclerosis and follow...
  3. Research Study: ITP and Lemtrada

    Please note: This is not a clinical trial of an intervention, but rather a research study. This is a single-visit research study, which can be performed at home or your physician’s office, to help determine the biomarkers that could potentially cause some users of LEMTRADA ...
  4. Clinical Trial: high intensity interval training

    The Exercise Psychophysiology Laboratory from the Department of Kinesiology at Berry College is recruiting for an exciting new study analyzing the effects of high intensity interval training on clinically relevant outcomes, like walking and cognition, in people with MS. The st...
  5. Clinical Trial: STEP for MS, an Exercise Intervention

    New research shows that exercise is good for people with MS and may decrease symptoms and improve health and walking ability. An exercise study called STEP for MS will compare the outcomes of a 16-week exercise program conducted at home to a program conducted in a gym. A train...
  6. Research Study: Seeking first degree relatives of people with MS for study of risk factors

    The goal of this study is to learn more about the causes of and risk factors for MS by studying first-degree relatives of people with MS and comparing them to people who are not first-degree relatives of someone with MS. We will use the data collected to develop a risk algorit...
  7. Clinical Trial: Emotion Regulation Skills Training

    Researchers are conducting a research study to help people with multiple sclerosis (MS) and their support partners learn skills for reducing symptoms of depression and anxiety and improving quality of life. Support partners can include significant others, friends, and family m...
  8. Clinical Trial: autologous hematopoietic stem cell transplantation (AHSCT)

    Investigators are recruiting 156 people with relapsing MS (relapsing-remitting MS or secondary progressive MS with relapses) at 19 sites nationwide for a pivotal clinical trial comparing autologous hematopoietic stem cell transplantation (AHSCT, also commonly known as HSCT) to...
  9. Clinical Trial: Physical Activity Class – Online Program

    Dr. Chung-Yi Chiu at the University of Illinois is conducting a study on lifestyle changes to increase physical activity levels for people with multiple sclerosis.   This 8 week program is led by peer coaches with MS who are experienced in a physically active lifestyle. Th...
  10. Clinical Trial: Computerized Cognitive Training

    The purpose of this study is to evaluate two computerized brain training tools, which include light physical activity, to see if they can help improve cognitive functions, such as memory and attention, for people with MS. Participants would complete a set of tests (physical an...
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