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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Lutein and Multiple Sclerosis Experimental Study (LuMES)

    The Body Composition and Nutritional Neuroscience lab at the University of Illinois at Urbana-Champaign is recruiting adults between 18-64 years with Multiple Sclerosis for a study that investigates the importance of nutrition for eye health and thinking ability among persons ...
  2. Clinical Trial: Effect of Disease Modifying Therapy on Antibody Response to COVID-19 Vaccination in People with MS

    The objective of the study is to determine whether certain disease modifying therapies impair or shorten immune responses to COVID-19 vaccines. The researchers are measuring antibody levels following vaccination with Moderna mRNA-1273 vaccine in people with MS. Therapies under...
  3. Clinical Trial: UCSF MS and COVID-19 Immunity Study

    MS treatment involves the use of medications that target the immune system, which can increase the risk of certain infections.  This study is being conducted to get a better understanding of how immunity to COVID-19 vaccination may be impacted by MS treatments.   Criteria fo...
  4. Clinical Trial: Immune responses to COVID vaccines in people with MS on ocrelizumab

    It is not know whether people receiving ocrelizumab for MS mount adequate immune responses to COVID-19 vaccine. The study is designed to investigate B-cell and T-cell responses to COVID-19 vaccination in patients treated with Ocrevus.  There are 5 visits for this study. All...
  5. Clinical Trial: Ocrelizumab in Progressive MS (CONSONANCE)

    The purpose of the study is to see if Ocrelizumab will halt the worsening of the signs and symptoms of Progressive forms of MS. Smartphone-based “passive monitoring” of participants will also take place during the study. It will collect data on gait and mobility throughout the...
  6. Clinical Trial: Ofatumumab for Patients with Relapsing Multiple Sclerosis

    MS study evaluating the continued effectiveness, safety and tolerability of Ofatumumab in adults, between the ages 18-60, with relapsing multiple sclerosis who are transitioning from traditional anti-CD20 therapy. Click on this link to answer a few questions to see if you q...
  7. Clinical Trial: Ocrelizumab in Black Americans and Hispanic/Latinx with Relapsing MS

    Investigators are recruiting 150 Black Americans and Hispanic/Latinx with relapsing MS to determine the effectiveness of  Ocrevus ®  (ocrelizumab) in these groups. The study, sponsored by Genentech, Inc., also is known as the CHIMES study. Read more
  8. Clinical Trial: Ozanimod to Improve Cognitive Function

     Investigators are recruiting 250 people with relapsing forms of MS for a clinical trial to determine if ozanimod (Zeposia ® , Bristol Myers Squibb) improves cognitive functions, specifically information processing speed. The study is funded by Celgene. Read more
  9. Clinical Trial: Nabiximols Oromucosal Spray for Spasticity

    Title:  A Double-blind, Randomized, Placebo-controlled, Parallel-group Trial of the Efficacy and Safety of Nabiximols Oromucosal Spray as Add-on Therapy in Patients with Spasticity Due to Multiple Sclerosis     Indication:  Symptomatic treatment of spasticity in patients wit...
  10. Clinical Trial: Enhancing Energy in MS (ENERGY Study)

    People with multiple sclerosis (MS) often have problems with fatigue. For some people, fatigue is their most debilitating symptom of MS. Yet, many of the available treatments provide inadequate relief for fatigue. Past research has found that training in self-hypnosis is linke...
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