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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Wearables for the Bladder

    This study is testing a solution for bladder problems in females with MS. Pelvic floor (a group of muscles and ligaments that support the bladder, uterus, and bowel) and bladder function will be assessed by a pelvic floor physical therapist as per standard care, and online ...
  2. Clinical Trial: ReCOVER – Clemastine Fumarate in Optic Neuritis

    WE ARE ACTIVELY RECRUITING PEOPLE EXPERIENCING A SUSPECTED OR DIAGNOSED ACUTE OPTIC NEURITIS IN A PREVIOUSLY UNAFFECTED EYE. VISUAL SYMPTOMS MUST BE WITHIN THE PAST 3 WEEKS AND THE PATIENT MUST BE STEROID NAIVE.  ReCOVER aims to assess the effect of Clemastine Fumarate as a...
  3. Research Study: Palm cooling after exercise

    This study measures and compares the amount of heat lost through the hands before, during, and after exercise, from two identical workouts. One workout sees persons with multiple sclerosis (MS) engage in palm cooling as they wear specialized gloves, while the other does no...
  4. Clinical Trial: Wheelchair Exercise-training for people with MS

    The purpose of this study is to examine the feasibility and initial efficacy of a novel exercise training program for people with MS who use wheelchairs. This intervention was developed with input from people with MS. If you choose to participate in this study, you will be ran...
  5. Clinical Trial: A phase 1 safety study of ANK-700 in people with relapsing-remitting MS

    Study Rationale: Multiple sclerosis (MS) is a neurological disease that causes damage to the brain and spinal cord, and steadily worsens over time. As the central nervous system (CNS) controls most body functions, people living with MS can experience a wide range of symptoms. ...
  6. Clinical Trial: A Telehealth tDCS Approach to Decrease Cannabis Use

    Researchers at NYU Langone Health, Multiple Sclerosis Comprehensive Care Center, are recruiting women with RRMS (ages 21 to 65) who regularly use any cannabis product (e.g., marijuana, edibles, vaping) and who wish to reduce cannabis use. The research study will be a one-month...
  7. Clinical Trial: An Online Physical Activity Lifestyle Program

    The Health Promotion and Rehabilitation Lab at the University of Illinois Urbana-Champaign is attempting to increase sustainable physically active lifestyle in this 8-week online program. To be eligible, participants must be,   18 years or older,   diagnosed with all su...
  8. Clinical Trial: Antioxidant for fatigue in MS and other studies

    Clinical Trial: Antioxidant for fatigue in MS Type of MS : ALL MS TYPES, RRMS PPMS, SPMS Treatment mode of action: ORAL Number of Subjects: 60 Medication: Mitoquinone (MitoQ, an antioxidant) Institution: Oregon Health Science University and Veterans Affairs Portland...
  9. Clinical Trial: Brain Shuttle CD20 inhibitor

    RO7121932 is being developed for the possible treatment of MS. RO7121932 combines a CD20 inhibitor antibody with a “brain shuttle” module, which delivers it to the brain.   This clinical trial is a phase 1 study, recruiting people who have multiple sclerosis, but have not ...
  10. Clinical Trial: Cannabidiol In People With MS: The Role Of Sleep And Pain (Cansleep-MS)

    Cannabidiol, the active ingredient in Epidiolex®, is a cannabinoid that naturally occurs in the Cannabis sativa L. plant.  Clinical trials suggest that cannabinoids (active compounds in Cannabis sativa) can be effective analgesics in individuals with chronic pain. Researche...
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