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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Gait Training

    Researchers at Indiana University Health seek adults who have a diagnosis of Primary or Secondary Progressive Multiple Sclerosis for a research study investigating the effects of gait and balance training on mobility and quality of life.     To participate, individuals mus...
  2. Clinical Trial: An online program to reduce depression

    SUMMARY: Investigators at three sites in the United States and two sites in Germany are recruiting 400 people with all forms of MS for a study testing the effectiveness of a computer training program for overcoming MS-related depression. The lead investigator is Stefan Gold, P...
  3. Clinical Trial: H.P. Acthar Gel®

    Investigators are recruiting 66 people with relapsing-remitting MS who have had a relapse and did not experience recovery from the relapse after high-dose intravenous or oral steroids. This study aims to determine the safety and effectiveness of H.P. Acthar Gel® (repository co...
  4. Clinical Trial: Balance Training

    We are investigating whether challenging balance while walking will improve walking and balance in people with MS. We are looking for volunteers whom have MS and experience balance problems, but do not need assistance for walking.   The study is held in our lab on Marquette Un...
  5. Clinical Trial: Ublituximab vs. Teriflunomide

     Investigators nationwide are recruiting 880 people with relapsing MS for two identical studies comparing ublituximab (TG Therapeutics, Inc.), an experimental monoclonal antibody administered via intravenous (into the vein) infusion, with oral teriflunomide.  The study is fund...
  6. Clinical Trial: Ofatumumab versus Teriflunomide

    The MS Center at EvergreenHealth is conducting a clinical trial to compare the effectiveness and safety of injections of ofatumumab administered every 4 weeks versus teriflunomide administered orally  once daily in patients with relapsing multiple sclerosis (MS). Eligible pa...
  7. Clinical Trial: ADS-5102 (amantadine)

    The MS Center at EvergreenHealth is conducting a research study of ADS-5102 (amantadine extended release [ER] capsules) for walking impairment in multiple sclerosis (MS). Patients with impaired walking may be eligible, but must able to complete a 25-foot timed walk (walking ai...
  8. Clinical Trial: Suvorexant for Fatigue and Insomnia

    The MS Center at EvergreenHealth is conducting a randomized, double-blind, placebo-controlled, cross-over trial to assess the safety, tolerability, and efficacy of suvorexant (Belsomra®) in treating insomnia in adults with multiple sclerosis (MS) and fatigue. This study will a...
  9. Clinical Trial: Immune Phenotype Biomarkers After Treatment With Fingolimod

    The MS Center at EvergreenHealth is conducting a study of immune phenotype biomarkers in patients with Relapsing Multiple Sclerosis (RMS) after treatment with 0.5mg fingolimod. This study uses a two-cohort, nonrandomized, open-label, multicenter design. The study consists of t...
  10. Clinical Trial: Behavioral Modification and Mirabegron for Urinary Urgency

    The EvergreenHealth MS Center is looking for subjects with multiple sclerosis (MS) and overactive bladder (bladder urgency or loss of bladder control) to participate in a 12-week study that combines behavioral modification with pelvic floor muscle strengthening exercises and o...

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