Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

NARCOMS Patient Registry

Register as a willing MS research participant to facilitate multicenter studies. Initiated by the Consortium of MS Centers.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

Clinical Trial: Brain Shuttle CD20 inhibitor

RO7121932 is being developed for the possible treatment of MS. RO7121932 combines a CD20 inhibitor antibody with a “brain shuttle” module, which delivers it to the brain. This clinical trial is a phase 1 study, recruiting people who have multiple sclerosis, but have not ...

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Clinical Trial: Cannabidiol In People With MS: The Role Of Sleep And Pain (Cansleep-MS)

Cannabidiol, the active ingredient in Epidiolex®, is a cannabinoid that naturally occurs in the Cannabis sativa L. plant. Clinical trials suggest that cannabinoids (active compounds in Cannabis sativa) can be effective analgesics in individuals with chronic pain. Researche...

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Clinical Trial: Comparing Experimental Fenebrutinib to Aubagio® in Relapsing MS

Investigators in the U.S. and abroad are recruiting a total of 1468 people with relapsing forms of MS for two separate studies comparing investigational oral fenebrutinib with Aubagio ® (teriflunomide, Sanofi Genzyme). The studies – also called FENhance – are sponsored by F....

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Clinical Trial: Comparing Experimental Tolebrutinib with Aubagio® in Relapsing MS

PLEASE NOTE: ENROLLMENT IN THIS STUDY HAS BEEN PLACED ON HOLD IN THE UNITED STATES BY THE FDA DUE TO SOME CASES OF LIVER INJURY. PLEASE SEE HERE FOR MORE INFORMATION. SUMMARY: Investigators are recruiting a total of 1800 people with relapsing forms of MS worldwide for ...

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Clinical Trial: Comparing Experimental Tolebrutinib with Placebo in Progressive MS

PLEASE NOTE: ENROLLMENT IN THIS STUDY HAS BEEN PLACED ON HOLD IN THE UNITED STATES BY THE FDA DUE TO SOME CASES OF LIVER INJURY. PLEASE SEE HERE FOR MORE INFORMATION. SUMMARY: Investigators in the U.S. and abroad are recruiting a total of 2280 people with progressive f...

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Clinical Trial: Computerized Cognitive Rehabilitation

This study examines a home-based computerized cognitive rehabilitation intervention focused on improving attention, learning, and memory in adults with MS, compared to a placebo intervention (a videogame). Enrolled participants will complete a series of mental ability eval...

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Clinical Trial: Effect of the Ataxia Crutch on walking in MS

I am recruiting adults with Multiple Sclerosis who currently walk using an assistive device (cane, walker, crutches, and trekking poles) to participate in a study. The goal of the study is to learn whether the Ataxia Balance Crutch is an effective device for people with MS. ...

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Clinical Trial: Efficacy of Diet on Quality of Life in MS

Please see below for travel reimbursement information. This is a research study comparing the effects of three diets — a Modified Paleolithic Diet (elimination of gluten, dairy, and eggs), a Time Restricted Olive Oil-based Ketogenic diet, and usual diet with informatio...

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Clinical Trial: Evaluating Mobility Interventions in the Real World

What is this study about? We want to study the best ways to help people walk and run better using lower-limb orthoses (leg braces). To do this, we will study people who use orthoses, as well as people who don’t. What will happen during the study? You might do an...

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Clinical Trial: Exercise Training Effects on Cognition and Brain Function in MS

This research study is examining the effects of exercise training in persons with multiple sclerosis who have been on any stable disease-modifying therapy for at least 6 months. The study is interested in examining the influence of supervised aerobic walking exercise or stretc...

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Participate in a Clinical Trial

Clinical Trials in MS

NARCOMS Patient Registry

Posting a Trial

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Clinical Trials In Your Area

Clinical Trial: Brain Shuttle CD20 inhibitor

Clinical Trial: Cannabidiol In People With MS: The Role Of Sleep And Pain (Cansleep-MS)

Clinical Trial: Comparing Experimental Fenebrutinib to Aubagio® in Relapsing MS

Clinical Trial: Comparing Experimental Tolebrutinib with Aubagio® in Relapsing MS

Clinical Trial: Comparing Experimental Tolebrutinib with Placebo in Progressive MS

Clinical Trial: Computerized Cognitive Rehabilitation

Clinical Trial: Effect of the Ataxia Crutch on walking in MS

Clinical Trial: Efficacy of Diet on Quality of Life in MS

Clinical Trial: Evaluating Mobility Interventions in the Real World

Clinical Trial: Exercise Training Effects on Cognition and Brain Function in MS

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The National MS Society is Here to Help

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