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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email to find out what information you need to submit for review.


Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: IMS001 in people with MS

    The purpose of this research is to determine the safety, tolerability, efficacy, and optimal dose regimen of an investigational human embryonic stem cell derived (hESC) mesenchymal stem cell (MSC) product to treat MS called IMS001.Taking part in this research will last for up ...
  2. Clinical Trial: Protective Step Training in People With MS

    Falls are common in people with multiple sclerosis (MS), and current rehabilitation approaches to reduce falls are inadequate. A novel and promising rehabilitation training program: Protective step training (in which a person is exposed to repeated "slips") has been developed ...
  3. Clinical Trial: Ozanimod for Cognitive Function

    This is a multicenter, single-arm, open-label study to describe the change from baseline in cognitive processing speed in subjects with relapsing multiple sclerosis (RMS) treated with ozanimod HCl 1 mg at 3 years. All enrolled subjects will receive orally administered ozanimod...
  4. Clinical Trial: Improving New Learning and Memory in MS

    The Kessler Foundation is currently recruiting for a study on memory. Participants will be compensated.. The study involves paper-and-pencil testing and is intended to assess the efficacy of learning and memory techniques within the Multiple Sclerosis population. Additionally,...
  5. Clinical Trial: Improving cognition in people with progressive MS

    Please note: The study sites for this trial are in Birmingham, AL, and East Hanover, NJ. Participation will require travel to those locations. Participants are people aged 25 to 65, with a diagnosis of progressive MS, who are not dependent on a wheelchair for mobility...
  6. Clinical Trial: Antioxidant for fatigue in MS and other studies

    Clinical Trial: Antioxidant for fatigue in MS Type of MS : ALL MS TYPES, RRMS PPMS, SPMS Treatment mode of action: ORAL Number of Subjects: 60 Medication: Mitoquinone (MitoQ, an antioxidant) Institution: Oregon Health Science University and Veterans Affairs Portland...
  7. Clinical Trial: EHP-101-MS02

    Brief Description The purpose of this study is to evaluate a new potential treatment for people living with Relapsing Forms of Multiple Sclerosis (RMS). Following the completion of a Phase 1 human clinical trial that assessed the safety and tolerability of different daily...
  8. Clinical Trial: remibrutinib vs. teriflunomide for relapsing multiple sclerosis

    Remibrutinib inhibits an enzyme called “Bruton’s tyrosine kinase,” reducing the activation of B cells, which are immune cells that play a role in the response that affects the brain and spinal cord in MS.  This study is for participants diagnosed with relapsing multiple scl...
  9. Clinical Trial: Reducing Fatigue and Restoring Energy to Support Health (REFRESH)

    PLEASE NOTE; THIS STUDY IS FULLY ENROLLED AND IS NO LONGER SEEKING PARTICIPANTS.  Description SUMMARY: A new research study is testing the effectiveness of an educational program that is delivered over the phone, internet, or videoconference.  Participating in the stu...
  10. Clinical Trial: Treadmill training to reduce falls

    Falls present a serious challenge facing individuals affected by multiple sclerosis. This study aims to examine if and to what extent slip-based training can reduce the risk of falls for people with multiple sclerosis. The researchers are seeking adults (18-65 years old) with ...
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