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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Pathological Basis of MRI Signal Changes in Multiple Sclerosis

    Multiple sclerosis (MS) is a disease that damages the central nervous system (brain and spinal cord). This leads to increased physical disability over time. The disease is lifelong once it begins. Researchers want to learn more about the stages of multiple sclerosis and follow...
  2. Research Study: ITP and Lemtrada

    Please note: This is not a clinical trial of an intervention, but rather a research study. This is a single-visit research study, which can be performed at home or your physician’s office, to help determine the biomarkers that could potentially cause some users of LEMTRADA ...
  3. Clinical Trial: high intensity interval training

    The Exercise Psychophysiology Laboratory from the Department of Kinesiology at Berry College is recruiting for an exciting new study analyzing the effects of high intensity interval training on clinically relevant outcomes, like walking and cognition, in people with MS. The st...
  4. Clinical Trial: STEP for MS, an Exercise Intervention

    New research shows that exercise is good for people with MS and may decrease symptoms and improve health and walking ability. An exercise study called STEP for MS will compare the outcomes of a 16-week exercise program conducted at home to a program conducted in a gym. A train...
  5. Research Study: Seeking first degree relatives of people with MS for study of risk factors

    The goal of this study is to learn more about the causes of and risk factors for MS by studying first-degree relatives of people with MS and comparing them to people who are not first-degree relatives of someone with MS. We will use the data collected to develop a risk algorit...
  6. Clinical Trial: Emotion Regulation Skills Training

    Researchers are conducting a research study to help people with multiple sclerosis (MS) and their support partners learn skills for reducing symptoms of depression and anxiety and improving quality of life. Support partners can include significant others, friends, and family m...
  7. Clinical Trial: Oral Siponimod

    To assess early phase safety and tolerability of converting from approved oral and injectable disease-modifying therapies for relapsing MS to siponimod. The results of this study will guide clinically relevant decisions related to the transition from frequently used therapies ...
  8. Clinical Trial: Electronic Pill Bottle

    People with MS have variable adherence to MS medications, making it challenging to determine the effectiveness of disease modifying therapies to assess true treatment failures. Whereas some people forget to take medications due to active lifestyles, others may have cognitive i...
  9. Research Study: looking at causes of fatiguing illness including MS

    This is an observational study looking at a symptomatic, immune function and inflammatory markers of disease with respect to fatiguing illnesses and their potential causes.  Participants will be asked to fill out a set of questionnaires, contribute saliva and blood, and have a...
  10. Clinical Trial: autologous hematopoietic stem cell transplantation (AHSCT)

    Investigators are recruiting 156 people with relapsing MS (relapsing-remitting MS or secondary progressive MS with relapses) at 19 sites nationwide for a pivotal clinical trial comparing autologous hematopoietic stem cell transplantation (AHSCT, also commonly known as HSCT) to...
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