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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis

    This study will evaluate the effectiveness and safety of ocrelizumab ( Ocrevus®) compared with placebo in participants with primary progressive multiple sclerosis (PPMS), including participants later in their disease course. This study focuses on upper limit disability progres...

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  2. Clinical Trial: Ocrelizumab vs. fingolimod in children and adolescents with MS

    Study is seeking to assess the safety and effectiveness of ocrelizumab (administered by intravenous infusion every 24 weeks) in comparison to fingolimod (one oral capsule taken once per day) in children and adolescents ages 10 to 18 with relapsing-remitting MS. The study is co...

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  3. Clinical Trial: Online Program to Increase Physical Activity in Persons Newly Diagnosed with MS

    Researchers at the University of Alabama at Birmingham are conducting an online behavior change intervention to promote lifestyle physical activity among persons diagnosed with MS within the last 2 years . The researchers aim to examine the effects of the program in helping...

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  4. Clinical Trial: Pathological Basis of MRI Signal Changes in Multiple Sclerosis

    Multiple sclerosis (MS) is a disease that damages the central nervous system (brain and spinal cord). This leads to increased physical disability over time. The disease is lifelong once it begins. Researchers want to learn more about the stages of multiple sclerosis and follow...

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  5. Clinical Trial: Physical therapy for balance

    We would like to investigate the use of motor imagery and physical practice on balance in persons with MS through the use of a home exercise program - this means practicing your balance training at home and NOT in a clinic.  Motor Imagery is imagining oneself performing a task...

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  6. Clinical Trial: Probiotic for Urinary Symptoms Among People Who Use Catheters (Remote)

    To qualify for this study you must be 18 years or older, use an indwelling catheter OR Intermittent catheter, be diagnosed with MS, and have a history of 2 or more episodes of urinary symptoms or infection in the past year. Researchers at MedStar National Rehabilitation Hos...

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  7. Clinical Trial: Protective Step Training in People With MS

    Falls are common in people with multiple sclerosis (MS), and current rehabilitation approaches to reduce falls are inadequate. A novel and promising rehabilitation training program: Protective step training (in which a person is exposed to repeated "slips") has been developed ...

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  8. Clinical Trial: ReWRAP: Remyelination for Women at Risk for Axonal Loss and Progression

    Dr. Riley Bove and her colleagues at the UCSF Multiple Sclerosis center are conducting a clinical trial to assess the efficacy of bazedoxifene (BZA) in promoting the repair of myelin (remyelination), an important insulating layer for neurons in the central nervous system a...

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  9. Clinical Trial: Robotic exoskeleton

    The purpose of this research study is to evaluate the usefulness of a wearable robotic exoskeleton (RE) device, called Ekso-GT, to improve learning, memory and walking ability in persons with walking disability due to Multiple Sclerosis. The study will evaluate the mobility, l...

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  10. Clinical Trial: STEP for MS, an Exercise Intervention

    New research shows that exercise is good for people with MS and may decrease symptoms and improve health and walking ability. An exercise study called STEP for MS will compare the outcomes of a 16-week exercise program conducted at home to a program conducted in a gym. A train...

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