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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: IMU-838 in Adults with Progressive MS

    This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate efficacy, safety, and tolerability of IMU-838 in people between 18 and 65 years old with primary or secondary progressive multiple sclerosis. Participants will be randomly assigned to receive...
  2. Clinical Trial: Mood and Exercise Training Study for Multiple Sclerosis

    METS for MS involves the remote delivery of a 4-month exercise training program with a 4-month follow-up period for persons with multiple sclerosis who have depression. The training programs involve either a combination of walking and resistance training or stretching. The exe...
  3. Clinical Trial: Behavioral intervention for MS (via Zoom)

    Researchers at Kessler Foundation are studying whether a series of online classes based on cognitive behavioral therapy and positive psychology principles may improve self-efficacy, coping, psychological well-being, and quality of life in MS. Participants are people who are di...
  4. Clinical Trial: Percutaneous Tibial Nerve Stimulation therapy for Women with MS

    Beaumont is conducting a research study to evaluate the effectiveness of percutaneous tibial nerve stimulation, or PTNS, to treat overactive bladder (OAB) symptoms in MS patients. The study is open to women over the age of 18 that have been diagnosed by a physician with Multip...
  5. Clinical Trial: Ukulele Playing to Improve Cognition in People With MS

    This study seeks to understand the impact that music can have on cognitive functioning and emotional well-being for people with MS. You may qualify for this study if you have MS, have cognitive deficits, and have access to a computer. If you are eligible and choose to particip...
  6. Clinical Trial: Zoom intervention for depression and anxiety

    Researchers at Kessler Foundation are studying whether an intervention aimed a treating depression and anxiety may result in improved psychological well-being, coping, and quality of life among individuals with multiple sclerosis (MS). Participation will involve attending 12 w...
  7. Clinical Trial: Virtual versus usual in-office care for MS

    SUMMARY The VIRTUAL-MS (Virtual versus usual in-office care for multiple sclerosis) study taking place at the Cleveland Clinic and the University of California San Francisco is comparing healthcare delivery via Telehealth and In-Person clinic visits. 120 people diagnosed wit...
  8. Clinical Trial: Mood and Exercise Training Study for MS

    METS for MS involves the remote delivery of a 4-month exercise training program with a 4-month follow-up period for persons with multiple sclerosis who have depression. The training programs involve either a combination of walking and resistance training or stretching. The ex...
  9. Clinical Trial: ReWRAP: Remyelination for Women at Risk for Axonal Loss and Progression

    Dr. Riley Bove and her colleagues at the UCSF Multiple Sclerosis center are conducting a clinical trial to assess the efficacy of bazedoxifene (BZA) in promoting the repair of myelin (remyelination), an important insulating layer for neurons in the central nervous system a...
  10. Clinical Trial: Efficacy of Diet on Quality of life in MS

    We are recruiting for a new study that is being conducted at the University of Iowa!  People affected by relapsing remitting multiple sclerosis who are between the ages of 18 and 70 are invited to participate to evaluate the effects of three diets — Modified Paleolithic Eli...
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