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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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NOTE: The COVID-19 pandemic may affect the status of the studies listed on this website. Trial recruitment or visits may be postponed, and responses from study coordinators may be delayed. If you are enrolled in a study, your study coordinator will likely reach out to you with any changes. Learn what you need to know about COVID-19

Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Hypnosis for Fatigue Management, English and Spanish

    Fatigue is a common, disabling, and debilitating symptom in individuals with MS. Research has shown that psychological treatments can help people with fatigue management and improve their quality of life. A common psychological treatment for fatigue is hypnosis. There are two ...
  2. Clinical Trial: Development of a Telehealth Obesity Intervention for People with MS

    This study is a behavioral telehealth program to help patients with MS who want to lose weight and live a healthier lifestyle.  Participants in this study will receive 24 weekly group phone counseling sessions. Each session will last approximately 60 minutes. In addition to...
  3. Clinical Trial: Electronic Pill Bottle

    People with MS have variable adherence to MS medications, making it challenging to determine the effectiveness of disease modifying therapies to assess true treatment failures. Whereas some people forget to take medications due to active lifestyles, others may have cognitive i...
  4. Research Study: Assessment of Portable Magnetic Resonance Imaging

    This study aims to examine the use of a novel portable MRI machine, which has been developed by physicists and physicians at the Massachusetts General Hospital. The MRI machine uses permanent magnets, meaning it doesn’t need liquid helium coolant, makes significantly less sou...
  5. Clinical Trial: Malignancies and MS Treatment

    VERISMO is a long-term, observational safety study of patients who are newly starting Ocrevus, or Lemtrada, Mavenclad, Tecfidera, Gilenya, Tysabri, or Aubagio. The goal of the study is to determine the full safety profile of Ocrevus compared to these other MS DMTs (disease mod...
  6. Clinical Trial: Cognitive Behavioral Therapy, Modafinil, or Both for MS Fatigue ("COMBO-MS")

    Many individuals with MS suffer from fatigue, which can be their most disabling symptom. Research is needed to figure out how to match treatments to individual patients so that the treatments will have the greatest effect.  This clinical trial will compare the effectivenes...
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