Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

NARCOMS Patient Registry

Register as a willing MS research participant to facilitate multicenter studies. Initiated by the Consortium of MS Centers.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

Clinical Trials: Transcranial Direct Current Stimulation Studies

Researchers at New York University are recruiting people with MS for three studies involving transcranial direct current stimulation (tDCS, which involves low electrical current delivered via electrodes). Clinical Trial: Neuroimaging with Transcranial Direct Current Stimulat...

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Clinical Trial: A Teleheath tDCS Approach to Decrease Cannabis Use

Researchers at NYU Langone Health, Multiple Sclerosis Comprehensive Care Center, are recruiting women with RRMS (ages 21 to 65) who regularly use any cannabis product (e.g., marijuana, edibles, vaping) and who wish to reduce cannabis use. The research study will be a one-month...

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Clinical Trial: Plant-Derived Oral Cannabinoid Spray to Treat Muscle Spasticity

SUMMARY: Investigators are recruiting 446 people with MS worldwide who are being treated for spasticity for a study testing whether adding nabiximols (an oral spray), to ongoing antispasticity therapy can reduce MS-related muscle spasms. The study is sponsored by Jazz Pharmace...

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Clinical Trial: Exploratory Study of Entire-body PET Scans for Multiple Sclerosis

Can an entire-body positron emission tomography (PET) scanner be used to improve evaluation, monitoring and measurement of both peripheral and central damage to nerve-insulating myelin (demyelination) in people with MS? We assume here that demyelination outside the brain may i...

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Clinical Trial: ReWRAP: Remyelination for Women at Risk for Axonal Loss and Progression

Dr. Riley Bove and her colleagues at the UCSF Multiple Sclerosis center are conducting a clinical trial to assess the efficacy of bazedoxifene (BZA) in promoting the repair of myelin (remyelination), an important insulating layer for neurons in the central nervous system a...

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Clinical Trial: Fenebrutinib

A study to evaluate the effectiveness and safety of fenebrutinib on disability progression and relapse rate. Eligible participants will be randomly assigned to receive either fenebrutinib or teriflunomide. Some may then receive fenebrutinib during an open label extension.

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Clinical Trial: Comparing Experimental Fenebrutinib to Aubagio® in Relapsing MS

Investigators in the U.S. and abroad are recruiting a total of 1468 people with relapsing forms of MS for two separate studies comparing investigational oral fenebrutinib with Aubagio ® (teriflunomide, Sanofi Genzyme). The studies – also called FENhance – are sponsored by F....

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Clinical Trial: Comparing Experimental Fenebrutinib to Ocrevus® in Primary Progressive MS

Investigators in the U.S. and abroad are recruiting 946 people with primary progressive MS for a study comparing investigational oral fenebrutinib with Ocrevus ® (ocrelizumab - Genentech, a member of the Roche Group). The study – also called FENtrepid – is sponsored by F. H...

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Clinical Trial: ofatumumab

A single-arm, prospective, multicentre, open-label study to evaluate ofatumumab treatment effectiveness and patient- reported outcomes in people with relapsing multiple sclerosis transitioning from dimethyl fumarate or fingolimod therapy. FDA Approved medication (Brand na...

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Clinical Trial: Behavioral intervention for MS (via Zoom)

Researchers at Kessler Foundation are studying whether a series of online classes based on cognitive behavioral therapy and positive psychology principles may improve self-efficacy, coping, psychological well-being, and quality of life in multiple sclerosis (MS). Participation...

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Participate in a Clinical Trial

Clinical Trials in MS

NARCOMS Patient Registry

Posting a Trial

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Clinical Trials In Your Area

Clinical Trials: Transcranial Direct Current Stimulation Studies

Clinical Trial: A Teleheath tDCS Approach to Decrease Cannabis Use

Clinical Trial: Plant-Derived Oral Cannabinoid Spray to Treat Muscle Spasticity

Clinical Trial: Exploratory Study of Entire-body PET Scans for Multiple Sclerosis

Clinical Trial: ReWRAP: Remyelination for Women at Risk for Axonal Loss and Progression

Clinical Trial: Fenebrutinib

Clinical Trial: Comparing Experimental Fenebrutinib to Aubagio® in Relapsing MS

Clinical Trial: Comparing Experimental Fenebrutinib to Ocrevus® in Primary Progressive MS

Clinical Trial: ofatumumab

Clinical Trial: Behavioral intervention for MS (via Zoom)

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Discover More

The National MS Society is Here to Help

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