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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Mood and Exercise Training Study for MS

    METS for MS involves the remote delivery of a 4-month exercise training program with a 4-month follow-up period for persons with multiple sclerosis who have depression. The training programs involve either a combination of walking and resistance training or stretching. The ex...

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  2. Clinical Trial: Mood and Exercise Training Study for Multiple Sclerosis

    METS for MS involves the remote delivery of a 4-month exercise training program with a 4-month follow-up period for persons with multiple sclerosis who have depression. The training programs involve either a combination of walking and resistance training or stretching. The exe...

    Get Details

  3. Clinical Trial: Motor Neuroprosthesis to restore motor control in people with severe impairment to both arms and legs

    The Synchron Motor NeuroProsthesis (MNP) is a brain-computer interface intended to improve functional independence and communication of healthcare needs for people who have impaired ability to move their arms and legs. This new device and surgical technique has been developed ...

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  4. Clinical trial: MS self-management app

    Many people with MS have been looking for a self-management app tailored to their needs in managing MS and health needs on their MS journey. Researchers at the University of Illinois worked with MS patients and clinicians to develop a new self-management app, SavvyHealth. We n...

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  5. Clinical Trial: Multiple Sclerosis Online Course

    Course duration: 24 July to 3 Sep 2023 Estimate effort: 1-2 hr per week Cost fee: Free Content: Introduction to MS, diet, vitamin D, exercise, mindfulness, medication, pregnancy, family & prevention Eligibility: Adults with diagnosed MS The MS Online Course study ...

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  6. Clinical Trial: Ocrelizumab for Preventing MS in Individuals With Radiologically Isolated Disease

    “Radiologically isolated syndrome” (RIS) is diagnosed when it is discovered that someone has brain MRI abnormalities similar in appearance and location to abnormalities seen in people with MS. People with RIS are typically otherwise healthy and without any symptoms common for ...

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  7. Clinical Trial: Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis

    This study will evaluate the effectiveness and safety of ocrelizumab ( Ocrevus®) compared with placebo in participants with primary progressive multiple sclerosis (PPMS), including participants later in their disease course. This study focuses on upper limit disability progres...

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  8. Clinical Trial: Ocrelizumab vs. fingolimod in children and adolescents with MS

    Study is seeking to assess the safety and effectiveness of ocrelizumab (administered by intravenous infusion every 24 weeks) in comparison to fingolimod (one oral capsule taken once per day) in children and adolescents ages 10 to 18 with relapsing-remitting MS. The study is co...

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  9. Clinical Trial: Online Program to Increase Physical Activity in Persons Newly Diagnosed with MS

    Researchers at the University of Alabama at Birmingham are conducting an online behavior change intervention to promote lifestyle physical activity among persons diagnosed with MS within the last 2 years . The researchers aim to examine the effects of the program in helping...

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  10. Clinical Trial: Pathological Basis of MRI Signal Changes in Multiple Sclerosis

    Multiple sclerosis (MS) is a disease that damages the central nervous system (brain and spinal cord). This leads to increased physical disability over time. The disease is lifelong once it begins. Researchers want to learn more about the stages of multiple sclerosis and follow...

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