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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email to find out what information you need to submit for review.


Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Protective Step Training in People With MS

    Falls are common in people with multiple sclerosis (MS), and current rehabilitation approaches to reduce falls are inadequate. A novel and promising rehabilitation training program: Protective step training (in which a person is exposed to repeated "slips") has been developed ...
  2. Clinical Trial: ReWRAP: Remyelination for Women at Risk for Axonal Loss and Progression

    Dr. Riley Bove and her colleagues at the UCSF Multiple Sclerosis center are conducting a clinical trial to assess the efficacy of bazedoxifene (BZA) in promoting the repair of myelin (remyelination), an important insulating layer for neurons in the central nervous system a...
  3. Clinical Trial: Robotic exoskeleton

    The purpose of this research study is to evaluate the usefulness of a wearable robotic exoskeleton (RE) device, called Ekso-GT, to improve learning, memory and walking ability in persons with walking disability due to Multiple Sclerosis. The study will evaluate the mobility, l...
  4. Clinical Trial: STEP for MS, an Exercise Intervention

    New research shows that exercise is good for people with MS and may decrease symptoms and improve health and walking ability. An exercise study called STEP for MS will compare the outcomes of a 16-week exercise program conducted at home to a program conducted in a gym. A train...
  5. Clinical Trial: Treatment Strategies to Prevent Disability

    A study based at Johns Hopkins University is comparing two treatment strategies in 900 people newly diagnosed, or with onset/diagnosis in the past who have received minimal or no treatment, with the relapsing-remitting form of MS. The study is recruiting at approximately 45 ce...
  6. Clinical Trial: Ukulele Playing to Improve Cognition in People With MS

    This study seeks to understand the impact that music can have on cognitive functioning and emotional well-being for people with MS. You may qualify for this study if you have MS, have cognitive deficits, and have access to a computer. If you are eligible and choose to particip...
  7. Clinical Trial: Virtual versus usual in-office care for MS

    SUMMARY The VIRTUAL-MS (Virtual versus usual in-office care for multiple sclerosis) study taking place at the Cleveland Clinic and the University of California San Francisco is comparing healthcare delivery via Telehealth and In-Person clinic visits. 120 people diagnosed wit...
  8. Clinical Trial: Zoom intervention for depression and anxiety

    Researchers at Kessler Foundation are studying whether an intervention aimed a treating depression and anxiety may result in improved psychological well-being, coping, and quality of life among individuals with multiple sclerosis (MS). Participation will involve attending 12 w...
  9. Clinical Trial:IMU-838

    Following a 4-week screening period, participants will take either oral IMU-838 or placebo for a period of 72 weeks during the main period of the study. Participants may need to stop taking certain MS medications during the trial.  An MRI scan will be needed during screening p...
  10. Clinical Trial: Brain stimulation for overactive bladder

    People with MS often experience a urinary bladder condition called Neurogenic Overactive Bladder (NOAB). People with NOAB often experience frequent urination, a sudden need to urinate, and even accidents. Instead of just focusing on the bladder, we want to see if we can improv...
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