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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email to find out what information you need to submit for review.


Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Home-Based Exercise Program for African Americans with MS (TEAAMS)

    The goal of the TEAAMS study is to examine whether a home-based exercise training program can provide improvements in walking dysfunction, symptoms, and quality of life among Black and African Americans with MS who live in the Southern US. Participants will exercise at their c...
  2. Clinical Trial: ReWRAP: Remyelination for Women at Risk for Axonal Loss and Progression

    Dr. Riley Bove and her colleagues at the UCSF Multiple Sclerosis center are conducting a clinical trial to assess the efficacy of bazedoxifene (BZA) in promoting the repair of myelin (remyelination), an important insulating layer for neurons in the central nervous system a...
  3. Clinical Trial: Pathological Basis of MRI Signal Changes in Multiple Sclerosis

    Multiple sclerosis (MS) is a disease that damages the central nervous system (brain and spinal cord). This leads to increased physical disability over time. The disease is lifelong once it begins. Researchers want to learn more about the stages of multiple sclerosis and follow...
  4. Research Study: Physical Activity and Biomarkers

    his pilot study examines if physical activity is associated with a blood biomarker of MS disease severity (neurofilament light chain), cognitive function, and vascular health in people with MS. Neurofilament light chain is a blood biomarker of damage in the central nervous sys...
  5. Research Study: Role of the Gut Microbiome in Depression in MS

    Investigators at Washington University in St. Louis are conducting a research study for people with multiple sclerosis (MS). The purpose of this study is to determine the potential effects of the gut microbiome on depression in MS. They are enrolling individuals with MS (inclu...
  6. Research Study: How Body Mass Composition Impacts Pediatric MS

    Study Description: MS researchers at the University of Virginia (UVA) & Children’s Hospital of Philadelphia (CHOP) seeks children, adolescents and young adults diagnosed with Pediatric-Onset Multiple Sclerosis within the past 3 years, and people without MS who are between ...
  7. Research Study: How lifestyle affects cognition

    Healthy lifestyle behaviors (e.g., exercise, cognitive stimulation, socialization) have been associated with maintaining cognitive health as we age. However, this has not be confirmed in the multiple sclerosis (MS) population. Therefore, the current study will investigate how ...
  8. Research Study: Portable MRI

    Researchers at the Massachusetts General Hospital are studying a portable MRI machine. Most MRI machines are extremely large, cost millions of dollars, and require specialized and expensive equipment to function. This portable MRI machine costs less than a traditional machine,...
  9. Research Study: Close Relatives of People with MS

    Researchers at Yale University are looking for close family members of people with MS to help them discover the earliest immune system changes that ultimately lead to Multiple Sclerosis (MS). Who can participate? Close relatives (parent, sibling, child) of someone with MS ...
  10. Research Study: MS and Aging

    Purpose of the study The goal of this research study is to evaluate how the brain is involved in walking in older adults with and without MS. The results will provide valuable new information about how brain structure and function affect the affect walking abilities and ri...
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