Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

NARCOMS Patient Registry

Register as a willing MS research participant to facilitate multicenter studies. Initiated by the Consortium of MS Centers.

Visit NARCOMS

Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

Clinical Trial: Nabiximols Oromucosal Spray for Spasticity

Title: A Double-blind, Randomized, Placebo-controlled, Parallel-group Trial of the Efficacy and Safety of Nabiximols Oromucosal Spray as Add-on Therapy in Patients with Spasticity Due to Multiple Sclerosis Indication: Symptomatic treatment of spasticity in patients wit...

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Clinical Trial: A safety study of ANK-700 in people with relapsing remitting MS

Investigators at 7 to 15 sites in the United States are recruiting approximately 33 people with relapsing-remitting MS to assess the safety of ANK-700. The study is divided into 2 parts, Part A and Part B. Please note - this is an in-person study. Precautions will be taken to ...

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Clinical Trial: Enhancing Energy in MS (ENERGY Study)

People with multiple sclerosis (MS) often have problems with fatigue. For some people, fatigue is their most debilitating symptom of MS. Yet, many of the available treatments provide inadequate relief for fatigue. Past research has found that training in self-hypnosis is linke...

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Clinical Trial: Ofatumumab

MS study to evaluate the effectiveness of ofatumumab after transitioning from oral therapy, in adults 18 to 60 with relapsing MS experiencing breakthrough disease. Study participation includes in-person visits, blood draws, MRI appointments, and use of electronic devices and ...

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Clinical Trial: Comparing Ocrevus® to Placebo for Slowing the Progression of Upper Limb Disability in People with Primary Progressive MS

nvestigators in the U.S. and abroad are recruiting 1000 people with primary progressive MS for a study comparing ocrelizumab (Ocrevus®) to placebo for slowing the progression of upper limb disability. The study – also called O’HAND – is sponsored by F. Hoffmann-La Roche. Rea...

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Clinical Trial: Living in Full Even (LIFE) with Pain Study

Chronic pain is a common and costly condition affecting millions of Americans. Chronic pain is also one of the most common symptoms associated with MS. Different types of treatment such as mindfulness meditation, cognitive therapy, and activation skills have been used to treat...

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Clinical Trial: Improving New Learning and Memory in MS

The Kessler Foundation is currently recruiting for a study on memory. Participants will be compensated.. The study involves paper-and-pencil testing and is intended to assess the efficacy of learning and memory techniques within the Multiple Sclerosis population. Additionally,...

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Clinical Trial: iSLEEPms: An Internet-Delivered Intervention for Sleep Disturbance in MS

This 12-week research study will evaluate a new web-based program, iSLEEPms, which is designed to help improve sleep in people with MS. This is a randomized controlled trial, where participants will be randomly assigned to complete the 4-week iSLEEPms program, or to continue t...

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Clinical Trial: Comparing Experimental Fenebrutinib to Ocrevus® in Primary Progressive MS

Investigators in the U.S. and abroad are recruiting 946 people with primary progressive MS for a study comparing investigational oral fenebrutinib with Ocrevus ® (ocrelizumab - Genentech, a member of the Roche Group). The study – also called FENtrepid – is sponsored by F. H...

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Clinical Trial: Comparing Experimental Fenebrutinib to Aubagio® in Relapsing MS

Investigators in the U.S. and abroad are recruiting a total of 1468 people with relapsing forms of MS for two separate studies comparing investigational oral fenebrutinib with Aubagio ® (teriflunomide, Sanofi Genzyme). The studies – also called FENhance – are sponsored by F....

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Participating in Clinical Trials

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Participate in a Clinical Trial

Clinical Trials in MS

NARCOMS Patient Registry

Posting a Trial

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Clinical Trials In Your Area

Clinical Trial: Nabiximols Oromucosal Spray for Spasticity

Clinical Trial: A safety study of ANK-700 in people with relapsing remitting MS

Clinical Trial: Enhancing Energy in MS (ENERGY Study)

Clinical Trial: Ofatumumab

Clinical Trial: Comparing Ocrevus® to Placebo for Slowing the Progression of Upper Limb Disability in People with Primary Progressive MS

Clinical Trial: Living in Full Even (LIFE) with Pain Study

Clinical Trial: Improving New Learning and Memory in MS

Clinical Trial: iSLEEPms: An Internet-Delivered Intervention for Sleep Disturbance in MS

Clinical Trial: Comparing Experimental Fenebrutinib to Ocrevus® in Primary Progressive MS

Clinical Trial: Comparing Experimental Fenebrutinib to Aubagio® in Relapsing MS

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Learn About Clinical Trials

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The National MS Society is Here to Help

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