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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Impact of Vancomycin on the Gut Microbiome and Immune Function in MS

    The goal of this study is to see if changes in the gut microbiome can alter multiple sclerosis outcomes.  Participants are newly diagnosed with MS (symptoms onset lest than 6 months) who have never taken disease-modifying treatment.  Participants will take vancomycin, an antib...
  2. Clinical Trial:IMU-838

    Following a 4-week screening period, participants will take either oral IMU-838 or placebo for a period of 72 weeks during the main period of the study. Participants may need to stop taking certain MS medications during the trial.  An MRI scan will be needed during screening p...
  3. Clinical Trial: Improving New Learning and Memory in MS

    The Kessler Foundation is currently recruiting for a study on memory. Participants will be compensated.. The study involves paper-and-pencil testing and is intended to assess the efficacy of learning and memory techniques within the Multiple Sclerosis population. Additionally,...
  4. Clinical Trial: Ocrelizumab for Preventing MS in Individuals With Radiologically Isolated Disease

    “Radiologically isolated syndrome” (RIS) is diagnosed when it is discovered that someone has brain MRI abnormalities similar in appearance and location to abnormalities seen in people with MS. People with RIS are typically otherwise healthy and without any symptoms common for ...
  5. Clinical Trial: An Online Physical Activity Lifestyle Program

    The Health Promotion and Rehabilitation Lab at the University of Illinois Urbana-Champaign is attempting to increase sustainable physically active lifestyle in this 8-week online program. To be eligible, participants must be,   18 years or older,   diagnosed with all su...
  6. Clinical Trial: Physical therapy for balance

    We would like to investigate the use of motor imagery and physical practice on balance in persons with MS through the use of a home exercise program - this means practicing your balance training at home and NOT in a clinic.  Motor Imagery is imagining oneself performing a task...
  7. Clinical Trial: Brain Shuttle CD20 inhibitor

    RO7121932 is being developed for the possible treatment of MS. RO7121932 combines a CD20 inhibitor antibody with a “brain shuttle” module, which delivers it to the brain.   This clinical trial is a phase 1 study, recruiting people who have multiple sclerosis, but have not ...
  8. Clinical Trial: Home-Based Exercise Program for African Americans with MS (TEAAMS)

    The goal of the TEAAMS study is to examine whether a home-based exercise training program can provide improvements in walking dysfunction, symptoms, and quality of life among Black and African Americans with MS who live in the Southeastern US. Participants will exercise at the...
  9. Clinical trial: MS self-management app

    Many people with MS have been looking for a self-management app tailored to their needs in managing MS and health needs on their MS journey. Researchers at the University of Illinois worked with MS patients and clinicians to develop a new self-management app, SavvyHealth. We n...
  10. Clinical Trial: Effect of the Ataxia Crutch on walking in MS

    I am recruiting adults with Multiple Sclerosis who currently walk using an assistive device (cane, walker, crutches, and trekking poles) to participate in a study. The goal of the study is to learn whether the Ataxia Balance Crutch is an effective device for people with MS.   ...
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