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Research Studies: Newly Diagnosed with MS

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Introduction

Without the help of people with MS, it would be impossible to develop new and better treatment interventions, or to unravel the mysteries of this disease. Some researchers are specifically trying to understand what happens in the earliest stages of MS for clues to stopping or preventing it. Here are several studies seeking participants who are new to MS.

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Watch  Ask an MS Expert: MS Clinical Trials – What You Need to Know
Download Participating in Clinical Trials: A Guide for People with MS

Behavior Change Program to Promote Physical Activity in People Newly Diagnosed with MS

Researchers at the University of Alabama at Birmingham are conducting a behavior change intervention to promote lifestyle physical activity among persons diagnosed with MS within the last 2 years.

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Detecting Early Signs of Cognitive Problems (New York)

Researchers at NYU Langone Health, Multiple Sclerosis Comprehensive Care Center, are partnering with individuals like you to discover ways to detect early signs of cognitive problems.
• We are recruiting individuals with an early diagnosis of, or at-risk, of developing MS.
• The research study consists of a single visit at the NYU Multiple Sclerosis Comprehensive Care Center.
• Participants will complete an MRI scan and a series of cognitive assessments, questionnaires, and an optional gait (walking) assessment.
• All study procedures are completed during a one-time visit.
• Compensation can be up to $125 for your time.

Participation in our research study is completely voluntary, free, and confidential.

For more information regarding enrollment, please contact us at 929-455-5090 or email us at NYUMSresearch@nyulangone.org
 

Trial of Treatment Strategies to Prevent Disability - TREAT MS

A study based at Johns Hopkins University is comparing two treatment strategies in 900 people newly diagnosed with relapsing-remitting MS, or with onset/diagnosis of relapsing-remitting MS in the past who have received minimal or no treatment. The study is recruiting at approximately 45 centers nationwide. One option is an escalation approach, in which people start taking a less powerful therapy with the option of switching to a more potent therapy if disease activity continues. The other approach involves starting with a stronger therapy that is potentially more effective, but also carries the potential for greater risk for significant adverse effects. The “TRaditional versus Early Aggressive Therapy for Multiple Sclerosis” (TREAT-MS) Trial is funded by the Patient-Centered Outcomes Research Institute (PCORI).

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Trial of Treatment Strategies to Prevent Disability - DELIVER MS

A study based at the Cleveland Clinic and the University of Nottingham (United Kingdom) is comparing two treatment strategies in 800 people with relapsing-remitting MS diagnosed within the past five years who have never taken a disease-modifying therapy. The study is recruiting at 30 centers in the United States and United Kingdom. One strategy is an “escalation” approach, in which individuals start taking a less-powerful therapy with the option of switching to a more potent one if disease activity continues. The other strategy involves starting with a strong therapy that is potentially more effective, but also carries greater risk for significant adverse effects. The “Determining the Effectiveness of Early Intensive versus Escalation Approaches for the Treatment of Relapsing-Remitting Multiple Sclerosis” (DELIVER-MS) Trial is funded by the Patient-Centered Outcomes Research Institute (PCORI).

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