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About this Medication
  • Brand Name:
  • Chemical Name: amantadine (a-man-ta-deen)
  • Usage in MS: Fatigue
  • Generic Available: Yes


Amantadine is an antiviral medication used to prevent or treat certain influenza infections; it is also given as an adjunct for the treatment of Parkinson's disease. It has been demonstrated that this amantadine, through some unknown mechanism, is sometimes effective in relieving fatigue in multiple sclerosis.

The usual dosage for the management of fatigue in MS is 100 to 200 mg daily, taken in the earlier part of the day in order to avoid sleep disturbance.

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© 2023 The National Multiple Sclerosis Society is a tax exempt 501(c)3 nonprofit organization. Its Identification Number (EIN) is 13-5661935.