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About this Medication
  • Brand Name: Aubagio® (U.S.)
  • Chemical Name: teriflunomide
  • Usage in MS: Disease-Modifying Agent
  • Generic Available: No

This is an oral medication in tablet form.



Aubagio® (teriflunomide), a pyrimidine synthesis inhibitor, is an oral compound that inhibits the function of specific immune cells that have been implicated in MS. It is related to leflunomide, a drug used to treat rheumatoid arthritis. Aubagio can inhibit a key enzyme required by white blood cells (lymphocytes) – which in turn reduces the proliferation of T and B immune cells that are active in MS and also inhibits the production of immune messenger chemicals by T cells.

Aubagio was approved by the U.S. Food and Drug Administration (FDA) in September, 2012 for relapsing forms of multiple sclerosis, which include clinically isolated syndrome, relapsing-remitting disease (RRMS) and active secondary progressive disease (SPMS with relapses).

Click here to see the FDA prescribing information for healthcare professionals.

Click here to see the FDA Medication Guide for patients.


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What You Need to Know About Aubagio®

Published January 11, 2013.
This video features Dr. Jim Bowen and Dr. Lily Jung Henson discussing approved disease-modifying treatment, Aubagio® (teriflunomide). To learn more about Aubagio® and other disease modifying treatment options, download the Consensus on Disease-Modifying Therapies and summary.

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