Onabotulinumtoxin A (BOTOX) is a powerful neurotoxin that temporarily blocks connections between the nerves and the muscles, resulting in short-term relaxation of the targeted muscle. Botox is administered by injection.
BOTOX is approved by the U.S. Food and Drug Administration (FDA) to treat:
- upper limb spasticity in adults, to relieve increased muscle tone in elbow flexors (biceps), wrist flexors, and finger flexors, including thumb flexor muscles. Upper limb spasticity can occur in MS as well as other disorders.
- lower limb spasticity in adults, to relieve increased muscle tone in ankle and toe flexors. Lower limb spasticity can occur in MS as well as other disorders.
- urinary incontinence resulting from overactivity of the bladder detrusor muscle caused by MS or other neurologic condition, in adults who have an inadequate response to anticholinergic medications or are unable to tolerate them.
Click here to read the BOTOX Prescribing Information for healthcare professionals.
Click here to read the BOTOX Medication Guide for patients.