- Brand Name: H.P. Acthar® (Repository Corticotropin) (U.S.)
- Chemical Name: Adrenocorticotropic hormone (ACTH)
- Usage in MS: Acute Exacerbations
- Generic Available: No
H.P. Acthar Gel is a highly purified preparation of adrenocorticotropic hormone (ACTH) in a gel that is designed to provide extended release of the ACTH following injection. ACTH stimulates the adrenal cortex gland to secrete cortisol, corticosterone, and aldosterone.
ACTH was approved in 1978 by the U.S. Food and Drug Administration (FDA) as a short-term treatment for acute exacerbations of MS. According to its FDA labeling, corticosteroids (such as methylprednisolone or dexamethasone) are considered the treatment of choice for acute exacerbations.
Click here to read the H.P. Acthar Gel Prescribing Information for healthcare professionals.
Click here to read the H.P. Acthar Gel Medication Guide for patients.