Skip to navigation Skip to content

Novantrone

Share

About this Medication
  • Brand Name: Novantrone® (U.S. and Canada)
  • Chemical Name: mitoxantrone for injection concentrate (mye-toe-ZAN-trone)
  • Usage in MS: Disease-Modifying Agent
  • Generic Available: Yes

This medication is given by IV infusion.

Description

Novantrone belongs to the general group of medicines called antineoplastics. Prior to its approval for use in MS, it was used only to treat certain forms of cancer. It acts in MS by suppressing the activity of T cells, B cells, and macrophages that are thought to lead the attack on the myelin sheath.

The U.S. Food and Drug Administration (FDA) has approved Novantrone for reducing neurologic disability and/or the frequency of clinical relapses (attacks) in:

  1. secondary progressive MS (disease that has changed from relapsing-remitting to progressive at a variable rate);
  2. progressive-relapsing MS (disease characterized by gradual increase in disability from onset with clear, acute relapses along the way);
  3. worsening relapsing-remitting MS (disease characterized by clinical attacks without complete remission, resulting in a step-wise worsening of disability.

Note: Novantrone has not been approved for the treatment of primary-progressive MS (characterized by progression from disease onset with no acute attacks or remissions).

Click here to read the Novantrone Prescribing Information for healthcare professionals.

Click here to read the Novantrone Medication Guide for patients.

Support

None available at this time.

Financial Assistance Program

No patient assistance program available at this time.



Share


© 2024 The National Multiple Sclerosis Society is a tax exempt 501(c)3 nonprofit organization. Its Identification Number (EIN) is 13-5661935.