- Brand Name: Pamelor (U.S.), Aventyl (Canada)
- Chemical Name: nortriptyline (nor-TRIP-ti-leen)
- Usage in MS: Pain (Paresthesias)
- Generic Available: Yes
Nortriptyline is a tricyclic antidepressant used to treat mental depression. In multiple sclerosis, it is frequently used to treat painful paraesthesias in the arms and legs (e.g., burning sensations, pins and needles, stabbing pains) caused by damage to the pain regulating pathways of the brain and spinal cord.
Note: Other tricyclic antidepressants also used for the management of neurological pain symptoms are: amitriptyline ( Elavil-U.S. and Canada), clomipramine (Anafranil-U.S. and Canada), desipramine (Norpramin-U.S. and Canada), doxepin (Sinequan-U.S. and Canada), imipramine (Tofranil-U.S. and Canada), trimipramine (U.S. and Canada).
Click here to read more about nortriptyline, which is also sold under the brand name Aventyl®.