- Brand Name: Tecfidera® (U.S.) (teck-fi-DARE-ah)
- Chemical Name: dimethyl fumarate (dye-METH-il FOO-mah-rate)
- Usage in MS: Disease-Modifying Agent
- Generic Available: Yes
This is an oral medication in capsule form.
Tecfidera® is an oral therapy contained in capsules taken two times per day. Tecfidera, formerly known as BG-12, is dimethyl fumarate, a formulation that was developed specifically for use by people with multiple sclerosis. A chemically related compound, called Fumaderm (dimethyl fumarate and fumaric acid esters), has been used at higher doses for decades in Germany to treat acute flare-ups of psoriasis. Although its exact mechanism of action is not known, Tecfidera is thought to modulate the immune response to be less inflammatory and may have antioxidant properties that could be protective against damage to the brain and spinal cord.
Tecfidera is approved by the FDA for the treatment of relapsing forms of multiple sclerosis to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease in adults.
Click here to read the Tecfidera Prescribing Information for healthcare professionals.
Click here to read the Tecfidera Patient Information.
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