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Medicines to Prevent and Treat COVID-19

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Some medicines to prevent COVID-19 pre-exposure and after exposure, as well as to treat COVID-19 infections, have been approved or authorized for use and are available now. Others are being tested. Refer to the National Institutes of Health and ClinicalTrials.gov for the most up-to-date information.

Pre-exposure prevention of COVID-19

Evusheld™

Updated: January 26, 2023
 
Evusheld is not authorized for use in the U.S. until further notice by the Food and Drug Administration.
 
Recent data show Evusheld is unlikely to be active against certain SARS-CoV-2 variants. These variants represent more than 90% of current infections in the U.S. This means that Evusheld is not expected to provide protection against developing COVID-19 if you are exposed to those variants.
 
To learn more and to stay abreast of news about Evusheld, refer to the FDA’s Drug Safety and Availability pages.

Post-exposure prevention of COVID-19

REGEN-COV

Updated: January 27, 2023

REGEN-COV is not authorized for use in the U.S. until further notice by the Food and Drug Administration.
 
Recent data show that the dominant variants of COVID-19 circulating now are resistant to REGEN-COV. This means that REGEN-COV is not currently expected to provide protection against developing COVID-19 if you are exposed to those variants.
 
To learn more, refer to the U.S. Department of Health and Human Services (HHS).

After contracting COVID-19

Various

The FDA has approved and authorized several treatments for COVID-19. If you have COVID-19, talk with your healthcare provider to determine if these medications are appropriate for you. Find treatment near you.

Early testing for COVID-19 and treatment with antiviral pills can prevent hospital stays. Test-to-Treat sites allow you to get tested as soon as you experience symptoms, get a prescription, if eligible, and start treatment. Find a Test-to-Treat site near you.

Additional resources

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